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  1. Article

    Open Access

    Genetic background impacts the timing of synaptonemal complex breakdown in Drosophila melanogaster

    Experiments performed in different genetic backgrounds occasionally exhibit failure in experimental reproducibility. This is a serious issue in Drosophila where there are no standard control stocks. Here, we illu...

    Emily R. Wesley, R. Scott Hawley, Katherine Kretovich Billmyre in Chromosoma (2020)

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  2. No Access

    Article

    Tetrad analysis in the mouse

    Meiotic tetrad analysis is a powerful tool for analyzing all four products of a single meiosis. A new method for tetrad analysis in mammals provides valuable insights into the mechanisms that mediate the excha...

    Danny E Miller, R Scott Hawley in Nature Genetics (2014)

  3. No Access

    Article

    RNF212 marks the spot

    A new study in mice shows that, during meiosis, the decision to mature a double-strand break into a crossover is controlled by a dosage-sensitive regulator, RNF212. This finding provides insight into the cross...

    Cathleen M Lake, R Scott Hawley in Nature Genetics (2013)

  4. No Access

    Chapter

    Synapsis, Double-Strand Breaks, and Domains of Crossover Control in Drosophila Females

    Drosophila is an attractive model system in which powerful tools in genetics and cytology can be used to identify and characterize the genes required for meiotic recombination. This ...

    Sonam Mehrotra, R. Scott Hawley, Kim S. McKim in Recombination and Meiosis (2008)

  5. No Access

    Article

    Homologous chromosome interactions in meiosis: diversity amidst conservation

  6. One of the unique aspects of meiosis is the pairing and exchange of information between homologous chromosomes.

  7. ...

    8. Jennifer L. Gerton, R. Scott Hawley in Nature Reviews Genetics (2005)

  8. No Access

    Article

    Hanging on to your homolog: the roles of pairing, synapsis and recombination in the maintenance of homolog adhesion

    Homologous chromosomes initially undergo weak alignments that bring homologous sequences into register during meiosis. These alignments can be facilitated by two types of mechanisms: interstitial homology sear...

    Michelle Y. Walker, R. Scott Hawley in Chromosoma (2000)

  9. No Access

    Article

    mei-41 is required for precocious anaphase in Drosophila females

    This paper reports on a new role for mei-41 in cell cycle control during meiosis. This function is revealed by the requirement of mei-41 for the precocious anaphase observed in crossover-defective mutants. Normal...

    K. S. McKim, J. K. Jang, J. J. Sekelsky, Anne Laurencon, R. Scott Hawley in Chromosoma (2000)

  10. No Access

    Article

    Spontaneous X chromosome MI and MII nondisjunction events in Drosophila melanogaster oocytes have different recombinational histories

    Recent studies of human oocytes have demonstrated an enrichment for distal exchanges among meiosis I (MI) nondisjunction events and for proximal exchanges among meiosis II (MII) events. Our characterization of...

    Kara E. Koehler, Christina L. Boulton, Heather E. Collins… in Nature Genetics (1996)

  11. No Access

    Article

    A structure-function analysis of NOD, a kinesin-like protein from Drosopbila melanogaster

    We have analyzed a collection of 12 mutations in the Drosophila melanogaster nod locus, which encodes a kinesin-like protein involved in female meiotic chromosome segregation. The kinesin-like domain is at the N-...

    Rebekah S. Rasooly, ** Zhang, Annette K. Tibolla… in Molecular and General Genetics MGG (1994)