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Open AccessDirect digital sensing of protein biomarkers in solution
The detection of proteins is of central importance to biomolecular analysis and diagnostics. Typical immunosensing assays rely on surface-capture of target molecules, but this constraint can limit specificity,...
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Assessing motor-related phenotypes of Caenorhabditis elegans with the wide field-of-view nematode tracking platform
Caenorhabditis elegans is a valuable model organism in biomedical research that has led to major discoveries in the fields of neurodegeneration, cancer and aging. Because movement phenotypes are commonly used and...
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Open AccessScalable integration of nano-, and microfluidics with hybrid two-photon lithography
Nanofluidic devices have great potential for applications in areas ranging from renewable energy to human health. A crucial requirement for the successful operation of nanofluidic devices is the ability to int...
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Article
Open AccessRapid two-dimensional characterisation of proteins in solution
Microfluidic platforms provide an excellent basis for working with heterogeneous samples and separating biomolecular components at high throughput, with high recovery rates and by using only very small sample ...
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Article
Open AccessMicrofluidic deposition for resolving single-molecule protein architecture and heterogeneity
Scanning probe microscopy provides a unique window into the morphology, mechanics, and structure of proteins and their complexes on the nanoscale. Such measurements require, however, deposition of samples onto...
