6 Result(s)
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Article
Open AccessPHB production from cellobiose with Saccharomyces cerevisiae
Replacement of petrochemical-based materials with microbially produced biodegradable alternatives calls for industrially attractive fermentation processes. Lignocellulosic materials offer non-edible alternativ...
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Chapter
Yeast Genome-Scale Metabolic Models for Simulating Genotype–Phenotype Relations
Understanding genotype–phenotype dependency is a universal aim for all life sciences. While the complete genotype–phenotype relations remain challenging to resolve, metabolic phenotypes are moving within the r...
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Article
Xylose-induced dynamic effects on metabolism and gene expression in engineered Saccharomyces cerevisiae in anaerobic glucose-xylose cultures
Xylose is present with glucose in lignocellulosic streams available for valorisation to biochemicals. Saccharomyces cerevisiae has excellent characteristics as a host for the bioconversion, except that it strongl...
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Chapter
Anaerobic Carbon Metabolism of Saccharomyces cerevisiae
The yeast Saccharomyces cerevisiae is a facultative anaerobic organism able to grow in the absence of oxygen. Oxygenation is one of the major costs in biotechnical production processes, and the anaerobic performa...
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Article
Open AccessMetabolic flux profiling of recombinant protein secreting Pichia pastoris growing on glucose:methanol mixtures
The methylotrophic yeast Pichia pastoris has emerged as one of the most promising yeast hosts for the production of heterologous proteins. Mixed feeds of methanol and a multicarbon source instead of methanol as s...
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Article
Open AccessCorrelation of gene expression and protein production rate - a system wide study
Growth rate is a major determinant of intracellular function. However its effects can only be properly dissected with technically demanding chemostat cultivations in which it can be controlled. Recent work on Sac...
