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Chapter
Renal Pathology
This chapter provides an introduction to the histological assessment of a medical renal biopsy, including an overview of the common pathological findings, an understanding of the pattern of injury, immunohisto...
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Chapter and Conference Paper
Sequential and Parallel Scattered Variable Neighborhood Search for Solving Nurikabe
Japanese pencil games have been the subjects of innumerable papers. However, some problems - like Sudoku - receive far more attention than others - like Nurikabe. In this paper we propose a novel algorithm to ...
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Article
Open AccessKaryomegalic interstitial nephritis with a novel FAN1 gene mutation and concurrent ALECT2 amyloidosis
Karyomegalic interstitial nephritis (KIN) is a rare hereditary cause of chronic kidney disease. It typically causes progressive renal impairment with haemoproteinuria requiring renal replacement therapy before...
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Article
Risk Factors for Recurrent Injuries from Physical Violence Among African Men in The Gambia
While men are known to be at high risk of recurrent injuries from physical violence, the risk factors in African men have not been investigated. We conducted a matched case-control study to identify factors as...
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Article
Open AccessMaternal overweight and obesity and the risk of caesarean birth in Malawi
Overweight and obese women are at risk of pregnancy and delivery complications. This study investigates the trend and association between maternal overweight and obesity on caesarean births in Malawi.
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Article
Open AccessCrescentic glomerulonephritis with anti-GBM antibody but no glomerular deposition
Anti-glomerular basement membrane (GBM) antibodies are highly specific for Goodpasture’s or anti-GBM disease, in which they are generally directed against the non-collagenous (NC1) domain of the alpha 3 chain ...
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Article
Open AccessPublisher Correction: Tubular iron deposition and iron handling proteins in human healthy kidney and chronic kidney disease
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
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Article
Open AccessTubular iron deposition and iron handling proteins in human healthy kidney and chronic kidney disease
Iron is suggested to play a detrimental role in the progression of chronic kidney disease (CKD). The kidney recycles iron back into the circulation. However, the localization of proteins relevant for physiolog...
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Article
Open AccessMaternal anemia is a potential risk factor for anemia in children aged 6–59 months in Southern Africa: a multilevel analysis
The effect of maternal anemia on childhood hemoglobin status has received little attention. Thus, we examined the potential association between maternal anemia and childhood anemia (aged 6–59 months) from sele...
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Article
Open AccessFainting Fanconi syndrome clarified by proxy: a case report
Rare diseases may elude diagnosis due to unfamiliarity of the treating physicians with the specific disorder. Yet, advances in genetics have tremendously enhanced our ability to establish specific and sometime...
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Article
Open AccessDNA fusion-gene vaccination in patients with prostate cancer induces high-frequency CD8+ T-cell responses and increases PSA doubling time
We report on the immunogenicity and clinical effects in a phase I/II dose escalation trial of a DNA fusion vaccine in patients with prostate cancer. The vaccine encodes a domain (DOM) from fragment C of tetanu...
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Article
Stem cell marker TRA-1-60 is expressed in foetal and adult kidney and upregulated in tubulo-interstitial disease
The kidney has an intrinsic ability to repair itself when injured. Epithelial cells of distal tubules may participate in regeneration. Stem cell marker, TRA-1-60 is linked to pluripotency in human embryonic st...
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Article
Acute renal failure in a patient with paroxysmal cold hemoglobinuria
Acute renal failure following auto-immune hemolysis is rare. We report a child with acute paroxysmal cold hemoglobinuria (PCH) complicated by renal failure. She was treated by peritoneal dialysis and red blood...
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Article
Tubulointerstitial nephritis and uveitis in monozygotic twin boys
We describe monozygotic male twins who developed tubulointerstitial nephritis and uveitis (TINU) almost 2 years apart. They presented with non-specific symptoms and were noted to have glycosuria and renal impa...
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Article
Intestinal Regrowth Is Amplified After Jejunal but Not Ileal Resection During Tapeworm Infection in the Rat
The ileum possesses functions required by a healthy individual that are not fully supplanted by the duodenum or jejunum. Evidence suggests that the ileum may also be necessary to maintain an enteric parasite–h...
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Article
The Effect of Local Attachment of Cationized Antioxidant Enzymes on Experimental Colitis in the Rat
Purpose. To investigate the possibility of local treatment of colitis with the adhesive antioxidant enzymes catalase and superoxide dismutase (SOD).
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Article
Relation Between Colonic Inflammation Severity and Total Low-Molecular-Weight Antioxidant Profiles in Experimental Colitis
Tissue antioxidant status is altered as a response to oxidative stress. This oxidative stress, caused by reactive oxygen species, is associated with inflammatory bowel disease (IBD). Our aim was to examine the...
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Article
Differences in the reducing power along the rat GI tract: Lower antioxidant capacity of the colon
The ability of the gastrointestinal (GI) tract, as well as other tissues, to cope with reactive oxygen species (ROS) efflux in pathological events is determined partly by epithelial antioxidant levels. These l...
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Article
Neuroplasticity in the smooth muscle of the myenterically and extrinsically denervated rat jejunum
The objective of this study was to examine the effects of two different denervation procedures on the distribution of nerve fibers and neurotransmitter levels in the rat jejunum. Extrinsic nerves were eliminat...
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Article
Plant regeneration by organogenesis in Vitis rootstock species
A procedure for the regeneration of Vitis rootstocks plantlets by organogenesis from foliar tissues is described. Leaves from mature plants grown in growth chambers or from plantlets grown in tubes were wounded w...
