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Article
The impact of patient activation on the effectiveness of digital health remote post-discharge follow-up and same-day-discharge after elective colorectal surgery
Low patient activation (PA) is associated with worse postoperative outcomes, however, its impact on the effectiveness of digital health interventions is unknown. We sought to determine the impact of PA on the ...
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Article
Does a multimodal prehabilitation program improve sleep quality and duration in patients undergoing colorectal resection for cancer? Pilot randomized control trial
Sleep difficulties are a common symptom in cancer patients at different stages of treatment trajectory and may lead to numerous negative consequences for which management is required. This pilot Randomized Con...
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Article
A retrospective analysis of early discharge following minimally invasive colectomy in an enhanced recovery pathway
There is increasing evidence to support discharge prior to gastrointestinal recovery following colorectal surgery. Furthermore, many patients are discharged early despite being excluded from an ambulatory cole...
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Article
Tolerating clear fluids diet on postoperative day 0 predicts early recovery of gastrointestinal function after laparoscopic colectomy
A high proportion of colorectal surgery patients within an enhanced recovery pathway (ERP) do not experience complications but remain hospitalized mainly waiting for gastrointestinal (GI) recovery. Accurate id...
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Article
Open AccessPeriodontal disease as a risk factor for sporadic colorectal cancer: results from COLDENT study
Colorectal cancer remains the top leading cancer worldwide. Accumulating evidence suggests periodontal pathogens are involved in colorectal carcinogenesis, indicating the need for high-quality epidemiological ...
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Article
Pelvic dimensions on preoperative imaging can identify poor-quality resections after laparoscopic low anterior resection for mid- and low rectal cancer
High-quality surgery is essential for optimal oncologic outcomes in rectal cancer, but total mesorectal excision (TME) can be difficult for mid- and low rectal cancers. Preoperative identification of patients ...
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Article
Intracorporeal versus extracorporeal anastomosis for right colectomy does not affect gastrointestinal recovery within an enhanced recovery after surgery program
Delayed gastrointestinal (GI) recovery remains a significant morbidity after colorectal surgery. Intracorporeal anastomosis for right colectomy may hasten GI recovery. Therefore, the objective of this study wa...
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Article
A mobile device application (app) to improve adherence to an enhanced recovery program for colorectal surgery: a randomized controlled trial
Increased adherence with enhanced recovery pathways (ERP) is associated with improved outcomes. However, adherence to postoperative elements that rely on patient participation remains suboptimal. Mobile device...
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Article
The Impact of Delays to Definitive Surgical Care on Survival in Colorectal Cancer Patients
Treatment delay may have detrimental effects on cancer outcomes. The impact of longer delays on colorectal cancer outcomes remains poorly described. The objective of this study was to determine the effect of d...
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Article
Does adherence to perioperative enhanced recovery pathway elements influence patient-reported recovery following colorectal resection?
Patient-reported outcome measures (PROMs) are pivotal to promote patient-centered perioperative care. Adherence to enhanced recovery programs (ERPs) is associated with improved clinical outcomes (i.e., morbidi...
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Article
Incidence and predictors of prolonged postoperative ileus after colorectal surgery in the context of an enhanced recovery pathway
Prolonged postoperative ileus (PPOI) is common after colorectal surgery but has not been widely studied in the context of enhanced recovery pathways (ERPs) that include interventions aimed to accelerate gastro...
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Article
Comparison between conventional colectomy and complete mesocolic excision for colon cancer: a systematic review and pooled analysis
Complete mesocolic excision (CME) is advocated based on oncologic superiority, but not commonly performed in North America. Many data are case series with few comparative studies. Our aim was to perform a syst...
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Article
An app for patient education and self-audit within an enhanced recovery program for bowel surgery: a pilot study assessing validity and usability
While patient engagement and clinical audit are key components of successful enhanced recovery programs (ERPs), they require substantial resource allocation. The objective of this study was to assess the valid...
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Article
Predictors of adherence to enhanced recovery pathway elements after laparoscopic colorectal surgery
Enhanced recovery pathways (ERP) include a bundle of evidence-based preoperative, intraoperative, and postoperative interventions that together reduce morbidity and length of stay after colorectal surgery. Inc...
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Article
Impact of adherence to care pathway interventions on recovery following bowel resection within an established enhanced recovery program
Guidelines recommend incorporation of more than 20 perioperative interventions within an enhanced recovery program (ERP). However, the impact of overall adherence to the pathway and the relative contribution o...
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Article
Open AccessV-Phaser 2: variant inference for viral populations
Massively parallel sequencing offers the possibility of revolutionizing the study of viral populations by providing ultra deep sequencing (tens to hundreds of thousand fold coverage) of complete viral genomes....
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Article
Impact of a trimodal prehabilitation program on functional recovery after colorectal cancer surgery: a pilot study
Patients undergoing colorectal cancer resections are at risk for delayed recovery. Prehabilitation aims to enhance functional capacity preoperatively for better toleration of surgery and to facilitate recovery...
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Article
Impact of an enhanced recovery program on short-term outcomes after scheduled laparoscopic colon resection
Both enhanced recovery programs (ERP) and laparoscopy can reduce complications and length of stay (LOS) in colon surgery. We investigated whether ERP further improved the short-term outcomes of scheduled lapar...
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Article
High incidence of symptomatic incisional hernia after midline extraction in laparoscopic colon resection
The incidence of incisional hernia has not decreased despite the use of laparoscopy for colon resections. The objective of this study is to evaluate the impact of the incision used for specimen extraction on t...
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Article
Open AccessDe novo assembly of highly diverse viral populations
Extensive genetic diversity in viral populations within infected hosts and the divergence of variants from existing reference genomes impede the analysis of deep viral sequencing data. A de novo population consen...
