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Chapter and Conference Paper
Broadband Terahertz Gas Spectroscopy Through Multimode Self-Mixing in a Quantum Cascade Laser
We present a self-mixing terahertz-frequency gas spectroscopy technique using a multimode quantum cascade laser. A precision-micro-machined external waveguide module and a double-metal quantum cascade laser de...
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Article
Open AccessTransporter gene acquisition and innovation in the evolution of Microsporidia intracellular parasites
The acquisition of genes by horizontal transfer can impart entirely new biological functions and provide an important route to major evolutionary innovation. Here we have used ancient gene reconstruction and f...
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Chapter and Conference Paper
Development of Terahertz Frequency Quantum Cascade Lasers for the Applications as Local Oscillators
We report the development of terahertz frequency quantum cascade lasers for applications as local oscillators. A range of active region designs and waveguide structures have been characterised in order to deve...
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Article
Open AccessHyponatremia and intensive care outcome
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Article
Open AccessAdmission to the ICU overnight: is it really a bad thing?
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Article
Open AccessHaemoglobin concentration on admission to intensive care influences hospital mortality rates and length of stay: a retrospective study
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Article
Using magnetic forces to enhance non-viral gene transfer to airway epithelium in vivo
We have assessed whether magnetic forces (magnetofection) can enhance non-viral gene transfer to the airways. TransMAGPEI, a superparamagnetic particle was coupled to Lipofectamine 2000 or cationic lipid 67 (GL67...
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Article
Estimation of premotor synaptic drives to simulated abducens motoneurons for control of eye position
The firing rate of an abducens motoneuron (AbMN) is linearly related to eye position with slope K, above recruitment threshold θ. Within the AbMN population K increases as θ increases. It is possible that these p...
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Article
Site-specific molecular design and its relevance to pharmacogenomics and chemical biology
The emergence of the new discipline of pharmacogenomics reflects the growing convergence of chemical and genomic space. The massive information-driven growth in both computational chemistry and structural biol...
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Article
Bellini duct (collecting duct) carcinoma of the kidney
Carcinoma of the collecting ducts, or Bellini carcinoma, is a rare renal tumour and, unlike most renal cell carcinomas, it derives from distal tubules. It displays highly aggressive behaviour and has a poor pr...
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Article
The effects of ozone and 1,8-cineole on sprouting, fry color and sugars of stored Russet Burbank potatoes
Ozone and 1,8-cineole were investigated as alternatives to isopropyl-n-(3-chloro-phenyl)carbamate (CIPC) to control sprout development of potato (Solatium tuberosum) tubers cv Russet Burbank during long-term stor...
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Article
Saccade control in a simulated robot camera-head system: neural net architectures for efficient learning of inverse kinematics
The high speed of saccades means that they cannot be guided by visual feedback, so that any saccadic control system must know in advance the correct output signals to fixate a particular retinal position. To i...
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Article
Output pathways from the rat superior colliculus mediating approach and avoidance have different sensory properties
Neuroanatomical studies have demonstrated that the two major descending pathways from the superior colliculus arise from regionally segregated, distinct, cells of origin. Stimulation and lesion studies have im...
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Article
N-methyl D-aspartate (NMDA) evoked changes in blood pressure and heart rate from the rat superior colliculus
Electrical stimulation and microinjections of the GABA antagonist bicuculline methiodide into the superior colliculus (SC) of the anaesthetized rat can evoke changes in blood pressure and heart rate. The long ...
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Article
The projection from superior colliculus to cuneiform area in the rat
Although the ipsilateral descending pathway is a major output projection of the superior colliculus, little is known of its functions. We therefore carried out two studies to investigate in rats the part of th...
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Article
The projection from superior colliculus to cuneiform area in the rat
To investigate the role of the projection from superior colliculus to the cuneiform nucleus in mediating collicular responses, the cuneiform area (including the cuneiform nucleus and immediately adjacent struc...
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Article
Descending projections from the superior colliculus in rat: a study using orthograde transport of wheatgerm-agglutinin conjugated horseradish peroxidase
Despite extensive behavioural work on the rat superior colliculus, its descending efferent pathways have not been fully characterised with modern anatomical tract-tracing techniques. To investigate these pathw...
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Article
Tectal cells of origin of predorsal bundle in rat: location and segregation from ipsilateral descending pathway
In rats, as in other mammals, one of the principal projections of the superior colliculus (SC) crosses the midline in the dorsal tegmental decussation to join the contralateral predorsal bundle (PDB). The cell...
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Article
Detection of visual stimuli in far periphery by rats: possible role of superior colliculus
Previous work has been shown that rats with lesions of the superior colliculus fail to respond to distracting visual stimuli presented in the peripheral field while the animals are running towards a central st...
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Article
Oral behaviour induced by intranigral muscimol is unaffected by haloperidol but abolished by large lesions of superior colliculus
It has been suggested that the GABAergic striatonigral projection may form part of the efferent pathway responsible for the expression of dopamine-related oral behaviour. Consistent with this suggestion are re...
