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  1. Article

    Open Access

    Van-Gogh-like 2 antagonises the canonical WNT pathway and is methylated in colorectal cancers

    Aberrant activation of the canonical WNT signaling is a feature of colorectal cancer (CRC). Van-Gogh-like 2 (VANGL2) belongs to the non-canonical WNT pathway whose activation inhibits canonical WNT signaling. ...

    G Piazzi, M Selgrad, M Garcia, C Ceccarelli, L Fini, P Bianchi… in British Journal of Cancer (2013)

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  2. Article

    Open Access

    The p53 codon 72 proline allele is endowed with enhanced cell-death inducing potential in cancer cells exposed to hypoxia

    The preferential retention of the arginine allele at the p53 codon 72 locus is commonly observed in tumours from arginine/proline heterozygotes. Considering that cancer cells are harboured in a hypoxic environ...

    P Sansone, G Storci, S Pandolfi, L Montanaro, P Chieco… in British Journal of Cancer (2007)

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  3. No Access

    Article

    Biopsying prostate gland: telomerase evaluation

    A Bertaccini, P Chieco, C Giovannini, I Capra… in Prostate Cancer and Prostatic Diseases (1999)

  4. No Access

    Article

    Basic strategies for valid cytometry using image analysis

    The present review provides a starting point for setting up an image analysis system for quantitative densitometry and absorbance or fluorescence measurements in cell preparations, tissue sections or gels. Gui...

    A. Jonker, W. J. C. Geerts, P. Chieco, A. F. M. Moorman… in The Histochemical Journal (1997)

  5. No Access

    Article

    The use of microfluorometry to study DNA in nasopharyngeal carcinomas: a possible prognostic tool?

    A microfluorometric method was used to determine the nuclear DNA content in the nasopharyngeal carcinomas (NPC) of 25 patients treated before 1983. Eleven patients are still alive with no evidence of disease (...

    U. Caliceti, A. Rinaldi Ceroni, G. Lisignoli… in Archives of oto-rhino-laryngology (1989)

  6. No Access

    Article

    Quantitative enzyme histochemistry of rat foetal brain and trigeminal ganglion

    The increasing concern and the efforts in determining neurological effects in offsprings resulting from maternal exposure to xenobiotics are faced with several difficulties in monitoring damage to the central ...

    P. Chieco, P. Hrelia, G. Lisignoli, G. Cantelli-forti in The Histochemical Journal (1988)

  7. No Access

    Chapter and Conference Paper

    Methadone Affects the Histochemical Pattern of Xenobiotic-Metabolizing Enzymes in the Liver of Pregnant Rats

    Enzyme histochemistry performed on the liver of pregnant and non pregnant rats indicates that methadone (ME) does not cause direct damage to the cells. On the other hand, the enzyme aldehyde dehydrogenase was ...

    P. Chieco, P. Hrelia, S. Candeletti… in Disease, Metabolism and Reproduction in th… (1984)

  8. No Access

    Chapter and Conference Paper

    Allylamine Cardiovascular Toxicity: Modulation of the Monoamine Oxidase System and Biotransformation to Acrolein

    Allylamine (3-aminopropene) is an aliphatic amine which is used in the production of drugs, antiseptics, and plastics. Many previous experimental studies have demonstrated the potent toxicity of allylamine tow...

    P. J. Boor, T. J. Nelson, M. T. Moslen… in Industrial and Environmental Xenobiotics (1981)