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Article
Open AccessUltra-fast deep-learned CNS tumour classification during surgery
Central nervous system tumours represent one of the most lethal cancer types, particularly among children1. Primary treatment includes neurosurgical resection of the tumour, in which a delicate balance must be st...
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Article
Open AccessMedulloblastoma in adults: evaluation of the Dutch society for neuro-oncology treatment protocol
Medulloblastoma is a rare tumor in adults. The objective of this nationwide, multicenter study was to evaluate the toxicity and efficacy of the Dutch treatment protocol for adult medulloblastoma patients.
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Article
Open AccessNTRK rearrangements in a subset of NF1-related malignant peripheral nerve sheath tumors as novel actionable target
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Article
Open AccessNon-invasively measured brain activity and radiological progression in diffuse glioma
Non-invasively measured brain activity is related to progression-free survival in glioma patients, suggesting its potential as a marker of glioma progression. We therefore assessed the relationship between bra...
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Article
Open AccessComputing three-dimensional two-phase flows with a mass-conserving level set method
A method is described to compute three- dimensional two-phase flow, allowing large density ratios and coalescence and break-up of bubbles. The level set method is used to describe interfaces, and the volume-of...
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Article
Open AccessSecondary meningioma in a long-term survivor of atypical teratoid/rhabdoid tumour with a germline INI1 mutation
We report on a patient who developed a meningioma more than two decades after removal at a young age of an atypical teratoid/rhabdoid tumour (AT/RT), which was due to a germline INI1 mutation, and radio- and chem...
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Article
Open AccessCharacterisation of tumour vasculature in mouse brain by USPIO contrast-enhanced MRI
To enhance the success rate of antiangiogenic therapies in the clinic, it is crucial to identify parameters for tumour angiogenesis that can predict response to these therapies. In brain tumours, one such para...
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Article
Open AccessLong-term survival and transmission of INI1-mutation via nonpenetrant males in a family with rhabdoid tumour predisposition syndrome
Rhabdoid tumour predisposition syndrome (RTPS) is a rare syndrome caused by inheritance of a mutated INI1 gene for which only two multigeneration families have been reported. To further characterise the genotype ...
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Article
Erratum to Progression of a Nelson’s adenoma to pituitary carcinoma; a case report and review of the literature