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Article
Open AccessNetwork Hyperexcitability in Early Alzheimer’s Disease: Is Functional Connectivity a Potential Biomarker?
Network hyperexcitability (NH) is an important feature of the pathophysiology of Alzheimer’s disease. Functional connectivity (FC) of brain networks has been proposed as a potential biomarker for NH. Here we u...
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Article
Open AccessMacroscale EEG characteristics in antipsychotic-naïve patients with first-episode psychosis and healthy controls
Electroencephalography in patients with a first episode of psychosis (FEP) may contribute to the diagnosis and treatment response prediction. Findings in the literature vary due to small sample sizes, medicati...
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Article
Open AccessNon-invasively measured brain activity and radiological progression in diffuse glioma
Non-invasively measured brain activity is related to progression-free survival in glioma patients, suggesting its potential as a marker of glioma progression. We therefore assessed the relationship between bra...
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Article
Open AccessCharacterization of symptoms and determinants of disease burden in dementia with Lewy bodies: DEvELOP design and baseline results
The DEmEntia with LEwy bOdies Project (DEvELOP) aims to phenotype patients with dementia with Lewy bodies (DLB) and study the symptoms and biomarkers over time. Here, we describe the design and baseline result...
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Article
Open AccessFunctional and effective whole brain connectivity using magnetoencephalography to identify monozygotic twin pairs
Resting-state functional connectivity patterns are highly stable over time within subjects. This suggests that such ‘functional fingerprints’ may have strong genetic component. We investigated whether the func...
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Article
Open AccessEndophenotypes in a Dynamically Connected Brain
We examined the longitudinal genetic architecture of three parameters of functional brain connectivity. One parameter described overall connectivity (synchronization likelihood, SL). The two others were derive...
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Article
Open AccessMEG resting state functional connectivity in Parkinson’s disease related dementia
Parkinson’s disease (PD) related dementia (PDD) develops in up to 60% of patients, but the pathophysiology is far from being elucidated. Abnormalities of resting state functional connectivity have been reporte...
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Chapter
6 Elektro-encefalogram (EEG)
Een elektro encefalogram (EEG) met diffuse afwijkingen ondersteunt bij twijfel de diagnose ziekte van Alzheimer.
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Article
Open AccessThe influence of low-grade glioma on resting state oscillatory brain activity: a magnetoencephalography study
Purpose In the present MEG-study, power spectral analysis of oscillatory brain activity was used to compare resting state brain activity in both low-grade glioma (LGG) patients and health...
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Chapter and Conference Paper
Observations on the cortical silent period in Parkinson’s disease
Transcranial magnetic stimulation is a tool in the neurosciences to study motor functions and nervous disorders, amongst others. Single pulses of TMS applied over the primary motor cortex lead to a so-called c...
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Article
EEG synchronisation during sleep-related epileptic seizures as a new tool to discriminate confusional arousals from paroxysmal arousals: preliminary findings
Confusional arousals, paroxysmal arousals (as part of the nocturnal frontal lobe epilepsy) and normal arousals and awakenings from NREM sleep are frequently a challenge for differential diagnosis. In this arti...
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Article
Localization of Fast MEG Waves in Patients with Brain Tumors and Epilepsy
It was investigated if single dipole analysis of spontaneous fast waves (>8 Hz) can be used to determine the location of the epileptic focus. Automatic dipole analysis was applied to MEG data of 25 patients wi...
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Article
EEG Correlates of Cerebral Engagement in Reading Tasks
This study evaluated the utility of electroencephalographic (EEG) measures as indices of regional cerebral engagement activation during reading in neurologically intact adult volunteers. EEG was recorded from ...
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Article
Investigation of the dynamics underlying periodic complexes in the EEG
Periodic complexes (PC), occurring lateralised or diffuse, are relatively rare EEG phenomena which reflect acute severe brain disease. The pathophysiology is still incompletely understood. One hypothesis sugg...
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Article
Non-linear analysis of the electroencephalogram in Creutzfeldt-Jakob disease
Creutzfeldt-Jakob disease is a rare, neurological, dementing disorder characterised by periodic sharp waves in the electroencephalogram (EEG). Non-linear analysis of these EEG changes may provide insight into...
