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  1. No Access

    Article

    Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study

    Genetic association studies of SLC6A4 (SERT) and obsessive-compulsive disorder (OCD) have been equivocal. We genotyped 1241 individuals in 278 pedigrees from the OCD Collaborative Genetics Study for 13 single-nuc...

    E Voyiaziakis, O Evgrafov, D Li, H-J Yoon, P Tabares, J Samuels… in Molecular Psychiatry (2011)

  2. No Access

    Article

    COMT genotype predicts cortical-limbic D1 receptor availability measured with [11C]NNC112 and PET

    A common polymorphism (val158met) in the gene encoding catechol-O-methyltransferase (COMT) has been shown to affect dopamine (DA) tone in cortex and cortical functioning. D1 receptors are the main DA receptors in...

    M Slifstein, B Kolachana, E H Simpson, P Tabares, B Cheng, M Duvall… in Molecular Psychiatry (2008)