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Chimiothérapie intra-artérielle hépatique, chimioembolisation et radioembolisation : un apport important pour le traitement des métastases hépatiques des cancers colorectaux
Les traitements locaux des métastases hépatiques (MH) des adénocarcinomes colorectaux (CCR) prennent une place de plus en plus importante dans les stratégies thérapeutiques des patients ayant des MH non réséca...
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Article
Adénocarcinome rectal six ans après chirurgie d’une duplication rectale kystique
La transformation maligne d’une duplication rectale est une situation exceptionnelle; le premier cas décrit dans la littérature remonte à 1932. Nous rapportons un nouveau cas de dégénérescence d’une duplicatio...
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Tumeurs digestives : côlon — rectum
Les cancers colorectaux (CCR) sont la deuxième cause de mortalité par cancer en France et un problème de santé publique [1]. La chirurgie est le traitement curatif de référence du CCR mais, pour les patients n...
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Les hépatogastroentérologues et la chimiothérapie en cancérologie digestive
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Open AccessTreatment of chronic low back pain with postural sagittal brace (LORDACTIV)
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Open AccessEarly detection of recurrence by 18FDG-PET in the follow-up of patients with colorectal cancer
We assessed the potential benefits of including systematic 18fluorodeoxyglucose positron emission tomography (FDG-PET) for detecting tumour recurrence in a prospective randomised trial. Patients (N=130) who had u...
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Isolated brainstem involvement in posterior reversible leukoencephalopathy induced by bevacizumab
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Traitements adjuvant et néoadjuvant des cancers du rectum
En cas de cancer du rectum, les objectifs principaux d’un traitement préopératoire sont de diminuer le risque de rechute locale, de permettre une chirurgie conservatrice et, si possible, d’améliorer la survie ...
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Article
Open AccessArterial phase enhancement and body mass index are predictors of response to chemoembolisation for liver metastases of endocrine tumours
Transcatheter arterial chemoembolisation (TACE) has been reported to be an efficient treatment of liver metastases of endocrine tumours in short series of patients. However, several factors seem to affect its ...
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Traitement adjuvant du cancer du pancréas
Le pronostic des cancers du pancréas (CP) résécables reste extrêmement péjoratif avec une survie à 5 ans de l’ordre de 4 %. La majorité des patients décèdent dans les 2 premières années du fait d’une récidive ...
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Article
Compatibility of postural behavior induced by two aspects of visual feedback: time delay and scale display
Fourteen healthy adults were tested to assess the potential influence on stance maintenance of two parts of the visual feedback technique (display scale and time delay). The task consisted in their kee** a s...
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Open AccessLoss of heterozygosity on 10q and mutational status of PTEN and BMPR1A in colorectal primary tumours and metastases
We investigated the possible role of chromosome 10q losses in colorectal cancer metastasis by carrying out an allelic imbalance study on a series of microsatellite instability-negative (MSI−) primary tumours (n=3...
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Article
Open AccessOral capecitabine vs intravenous 5-fluorouracil and leucovorin: integrated efficacy data and novel analyses from two large, randomised, phase III trials
This study evaluates the efficacy of capecitabine using data from a large, well-characterised population of patients with metastatic colorectal cancer (mCRC) treated in two identically designed phase III studi...
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Open AccessCarcinoma of the colon
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Open AccessHepatocellular carcinoma
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Open AccessCarcinoma of the oesophagus
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Open AccessCancer of the rectum
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Open AccessPrognostic factors for tumour response, progression-free survival and toxicity in metastatic colorectal cancer patients given irinotecan (CPT-11) as second-line chemotherapy after 5FU failure
Our purpose was to determine, in patients with metastatic colorectal carcinoma treated with irinotecan single-agent after 5-FU failure, the most significant predictive parameters for tumour response, progressi...
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Article
Open AccessExtensive molecular screening for hereditary non-polyposis colorectal cancer
The genetic abnormalities underlying hereditary non-polyposis colorectal cancer (HNPCC) are germline mutations in one of five DNA mismatch repair genes or in the TGFβRII gene. The aim of our study was to evaluate...
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Article
Open AccessTreatment of poorly differentiated neuroendocrine tumours with etoposide and cisplatin
The purpose of this study was to evaluate by a retrospective analysis of 53 patients the efficacy of chemotherapy combining etoposide and cisplatin in the treatment of neuroendocrine tumours. The regimen was a...
