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  1. Article

    Standards of Scoring, Monitoring, and Parameter Targeting in German Neurocritical Care Units: A National Survey

    Optimal management of physiological parameters in neurological/neurosurgical intensive care units (NICUs) is largely unclear as high-quality evidence is lacking. The aim of this survey was to investigate if st...

    C. M. Kowoll, C. Dohmen, J. Kahmann, R. Dziewas, I. Schirotzek… in Neurocritical Care (2014)

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    Chapter

    Erhöhter intrakranieller Druck

    Der Inhalt des Neurokraniums besteht aus dem weichen Hirngewebe, den bindegewebigen Hirnhäuten und -gefäßen (kompressibles Kompartiment) sowie den Flüssigkeiten Liquor und Blut (inkompressibles Kompartiment). ...

    O.W. Sakowitz, A.W. Unterberg in Die Intensivmedizin (2008)

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    Chapter and Conference Paper

    Neuronal activity and cortical perfusion determined by quantitative EEG analysis and laser Doppler flowmetry are uncoupled in brain injured rats

    Following traumatic brain injury uncoupling of metabolism from perfusion, reflected by an increase in cellular activity in face of reduced perfusion contributes to secondary tissue damage.

    J. F. Stover M.D, O. W. Sakowitz… in Mechanisms of Secondary Brain Damage from … (2004)

  4. No Access

    Chapter

    Erhöhter intrakranieller Druck

    Der Inhalt des Neurokrniums besteht uas weichen Hirngewebe, den bindegewebigen Hirnhäuten und -gefäßen (kompressibles Kompartiment) sowie den Flüssigkeiten Liquor und Blut (inkompressibles Kompartiment). Bei...

    A. W. Unterberg, O. W. Sakowitz in Die Intensivmedizin (2004)

  5. No Access

    Chapter and Conference Paper

    Detection of Secondary Insults by Brain Tissue pO2 and Bedside Microdialysis in Severe Head Injury

    We evaluated bedside cerebral on-line microdialysis for early detection of cerebral hypoxia in patients with traumatic brain injury. 24 severely head injured patients (Glasgow Coma Score ≤ 8) were studied. Pat...

    Asita S. Sarrafzadeh, O. W. Sakowitz… in Intracranial Pressure and Brain Biochemica… (2002)

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    Chapter and Conference Paper

    Norepinephrine is Superior to Dopamine in Increasing Cortical Perfusion Following Controlled Cortical Impact Injury in Rats

    Following traumatic brain injury catecholamines are routinely applied to increase cerebral perfusion. To date, it remains controversial if infusion of catecholamines is associated with diminished cerebral perf...

    S.-N. Kroppenstedt, O. W. Sakowitz… in Intracranial Pressure and Brain Biochemica… (2002)

  7. No Access

    Chapter and Conference Paper

    Neuronal Activity Determined by Quantitative EEG and Cortical Microdialysis is Increased Following Controlled Cortical Impact Injury in Rats

    Following brain injury increased glutamate release is linked to sustained neuronal activation resulting in excitotoxic tissue damage. Isoflurane anesthesia has been shown to decrease electroencephalo-graphic (...

    O. W. Sakowitz, A. W. Unterberg… in Intracranial Pressure and Brain Biochemica… (2002)

  8. No Access

    Chapter and Conference Paper

    Time Course of Various Interstitial Metabolites Following Subarachnoid Hemorrhage Studied by on-Line Microdialysis

    Subarachnoid hemorrhage (SAH) is one of the most devastating of all cerebrovascular disorders [10]. One of the most serious complications of SAH remains vasospasm [3, 9]. Bedside cerebral microdialysis is a recen...

    A. S. Sarrafzadeh, O. W. Sakowitz, W. R. Lanksch, A. W. Unterberg in Cerebral Vasospasm (2001)