7 Result(s)

Article

Aprepitant for refractory cutaneous T-cell lymphoma-associated pruritus: 4 cases and a review of the literature

Aprepitant is an FDA-approved medication for chemotherapy-induced nausea and vomiting. It blocks substance P binding to neurokinin-1; substance P has been implicated in itch pathways both as a local and global...

Johanna S. Song, Marianne Tawa, Nicole G. Chau, Thomas S. Kupper… in BMC Cancer (2017)

Article

Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations

Nasopharyngeal carcinoma (NPC) is an aggressive head and neck cancer characterized by Epstein-Barr virus (EBV) infection and dense lymphocyte infiltration. The scarcity of NPC genomic data hinders the understa...

Yvonne Y Li, Grace T. Y. Chung, Vivian W. Y. Lui, Ka-Fai To… in Nature Communications (2017)

Article

Definitive chemoradiation alters the immunologic landscape and immune checkpoints in head and neck cancer

Preclinical and clinical studies suggest potential synergy between high dose per fraction focal radiation and immunotherapy. However, conventionally fractionated radiation regimens in combination with concurre...

Vishwajith Sridharan, Danielle N Margalit, Stephanie A Lynch… in British Journal of Cancer (2016)

Article

Immunologic profiling of adenoid cystic carcinoma (acc)

Vishwajith Sridharan, **aoyun Liao, Nicole G Chau… in Journal for ImmunoTherapy of Cancer (2015)

Article

Early mortality and overall survival in oncology phase I trial participants: can we improve patient selection?

Patient selection for phase I trials (PIT) in oncology is challenging. A typical inclusion criterion for PIT is 'life expectancy > 3 months', however the 90 day mortality (90DM) and overall survival (OS) of pa...

Nicole G Chau, Ana Florescu, Kelvin K Chan, Lisa Wang, Eric X Chen… in BMC Cancer (2011)

Article

The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck

We examine the potential prognostic and predictive roles of EGFR variant III mutation, EGFR gene copy number (GCN), human papillomavirus (HPV) infection, c-MET and p16 ^INK4A

Nicole G Chau, Bayardo Perez-Ordonez, Katherine Zhang, Nhu-An Pham… in Head & Neck Oncology (2011)