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Article

Early mortality and overall survival in oncology phase I trial participants: can we improve patient selection?

Patient selection for phase I trials (PIT) in oncology is challenging. A typical inclusion criterion for PIT is 'life expectancy > 3 months', however the 90 day mortality (90DM) and overall survival (OS) of pa...

Nicole G Chau, Ana Florescu, Kelvin K Chan, Lisa Wang, Eric X Chen… in BMC Cancer (2011)