25 Result(s)
within
Ni **-ren
Cancer Research
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Article
Open AccessDeciphering the role of zinc homeostasis in the tumor microenvironment and prognosis of prostate cancer
Dysregulation of zinc homeostasis is widely recognized as a hallmark feature of prostate cancer (PCa) based on the compelling clinical and experimental evidence. Nevertheless, the implications of zinc dyshomeo...
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Open AccessPlasma exosomes contain protein biomarkers valuable for the diagnosis of lung cancer
Accumulating evidence indicates that exosomal proteins are critical in diagnosing malignant tumors. To identify novel exosomal biomarkers for lung cancer diagnosis, we isolated plasma exosomes from 517 lung ca...
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Risk factors of perforation in gastric stromal tumors during endoscopic resection: a retrospective case–control study
Perforation is a common complication during endoscopic resection (ER) of gastric gastrointestinal stromal tumors (gGISTs) associated with secondary infections, sepsis, hospitalization time and cost. However, t...
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Open AccessProtamine 1 as a secreted colorectal cancer-specific antigen facilitating G1/S phase transition under nutrient stress conditions
Cancer testis antigens (CTAs) are optimal tumor diagnostic markers and involved in carcinogenesis. However, colorectal cancer (CRC) related CTAs are less reported with impressive diagnostic capability or relev...
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Open AccessInnate immune imprints in SARS-CoV-2 Omicron variant infection convalescents
SARS-CoV-2 Omicron variant infection generally gives rise to asymptomatic to moderate COVID-19 in vaccinated people. The immune cells can be reprogrammed or “imprinted” by vaccination and infections to generat...
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Open AccessCDC6 is a prognostic biomarker and correlated with immune infiltrates in glioma
Cell division cycle 6 (CDC6) has been proven to be associated with the initiation and progression of human multiple tumors. However, it’s role in glioma, which is ranked as one of the common primary malignant ...
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Open AccessN6-methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma
Sunitinib resistance can be classified into primary and secondary resistance. While accumulating research has indicated several underlying factors contributing to sunitinib resistance, the precise mechanisms i...
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Risk of prostate cancer in men with HIV/AIDS: a systematic review and meta-analysis
Although previous studies have shown a decreased incidence of prostate cancer in men with HIV/AIDS, the consensus has not been reached. Our aim is to conduct a systematic review and meta-analysis to assess the...
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Open AccessPatients with pretreatment leukoencephalopathy and older patients have more cognitive decline after whole brain radiotherapy
To investigate predictors of cognitive decline after whole brain radiotherapy (WBRT) for brain metastases.
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Open AccessThe fiber metabolite butyrate reduces gp130 by targeting TRAF5 in colorectal cancer cells
Dietary fiber is effective for colorectal cancer (CRC) treatment. Interleukin-6 (IL-6) and its adaptors are potential targets for CRC therapy. Butyrate, a metabolite of dietary fiber, is a new, highly safe typ...
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Antibody responses to SARS-CoV-2 in patients with COVID-19
We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG...
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Diagnostic Model of Serum miR-193a-5p, HE4 and CA125 Improves the Diagnostic Efficacy of Epithelium Ovarian Cancer
Epithelium ovarian cancer (EOC) is currently the prevalent malignant cancer worldwide. However, there is a lack of efficient biomarkers for EOC screening. Accumulating evidence reveals that serum miRNA detecta...
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Open AccessBreast cancer risk factors and mammographic density among high-risk women in urban China
Elevated mammographic density (MD) is an established breast cancer risk factor. Studies examining relationships between MD and breast cancer risk factors are limited in China, where established breast cancer r...
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Open AccessThe association between fasting blood glucose and the risk of primary liver cancer in Chinese males: a population-based prospective study
To investigate the association between fasting blood glucose (FBG) levels and the risk of incident primary liver cancer (PLC) in Chinese males, a large prospective cohort was performed in the current study.
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Open AccessExpenditure and financial burden for the diagnosis and treatment of colorectal cancer in China: a hospital-based, multicenter, cross-sectional survey
The increasing prevalence of colorectal cancer (CRC) in China and the paucity of information about relevant expenditure highlight the necessity of better understanding the financial burden and effect of CRC di...
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HLA-DP is the cervical cancer susceptibility loci among women infected by high-risk human papillomavirus: potential implication for triage of human papillomavirus-positive women
Given that only a small proportion of women infected by high-risk human papillomavirus (hrHPV) develop cervical cancer, it’s important to identify biomarkers for distinguishing women with hrHPV positivity who ...
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Combretastatin A4 phosphate treatment induces vasculogenic mimicry formation of W256 breast carcinoma tumor in vitro and in vivo
The purpose of this study was to investigate the effect of combretastatin A4 phosphate (CA4P) on vasculogenic mimicry (VM) channel formation in vitro and in vivo after a single-dose treatment and the underlyin...
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Open AccessBevacizumab promotes venous thromboembolism through the induction of PAI-1 in a mouse xenograft model of human lung carcinoma
An increased incidence of venous thromboembolism (VTE) is associated with anti-vascular endothelial growth factor (VEGF) treatment in cancer. However, the mechanism underlying this effect remains elusive. In t...
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Open AccessInternational trends in primary liver cancer incidence from 1973 to 2007
Primary liver cancer (PLC) is a common cancer worldwide, especially in develo** countries. Several previous studies using different datasets have summarized PLC incidence rates and trends in different popula...
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Open AccessPresence of intratumoral platelets is associated with tumor vessel structure and metastasis
Platelets play a fundamental role in maintaining hemostasis and have been shown to participate in hematogenous dissemination of tumor cells. Abundant platelets were detected in the tumor microenvironment outsi...
