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Article
Open AccessClinical development of mRNA therapies against solid tumors
The mRNA-based therapeutics have become the hot spot of biopharmaceutical industries in recent years. The landscape of this area is expanding from infectious disease to cancer, which needs to be summarized to ...
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Article
Open AccessIntegrating China in the international consortium for personalised medicine. a position paper on healthcare professionals’ education and citizens’ empowerment in personalised medicine
Personalised medicine (PM) has been fostered by technological and medical advances, but all stakeholders, including healthcare professionals, citizens and policy makers, should achieve adequate health literacy...
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Article
Open AccessMedical expenditure for lung cancer in China: a multicenter, hospital-based retrospective survey
Lung cancer is the most prevalent cancer, and the leading cause of cancer-related deaths in China. The aim of this study was to estimate the direct medical expenditure incurred for lung cancer care and analyze...
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Article
Open AccessMedical expenses of urban Chinese patients with stomach cancer during 2002–2011: a hospital-based multicenter retrospective study
In China, stomach cancer is the third most common cancer and the third leading cause of cancer death. Few studies have examined Chinese stomach cancer patients’ medical expenses and their associated trends. Th...
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Article
Open AccessMedical expenditure for esophageal cancer in China: a 10-year multicenter retrospective survey (2002–2011)
Esophageal cancer is associated with substantial disease burden in China, and data on the economic burden are fundamental for setting priorities in cancer interventions. The medical expenditure for the diagnos...
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Article
Open AccessExpenditure and financial burden for the diagnosis and treatment of colorectal cancer in China: a hospital-based, multicenter, cross-sectional survey
The increasing prevalence of colorectal cancer (CRC) in China and the paucity of information about relevant expenditure highlight the necessity of better understanding the financial burden and effect of CRC di...
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Article
A tandem enzymatic hydrolysis of 3-acetylthio-2-methylpropionic methy ester
Enzymatic hydrolysis of racemic 3-acetylthio-2-methylpropionic methyl ester catalyzed by bovine pancreatic protease and Mucor javanicus lipase showed opposite enantioselecivity. A tandem hydrolysis of the ester c...
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Article
Papain catalyzed synthesis of unsymmetric cystine peptides
Immobilized papain catalyzed the coupling of N,N′-diBoc-cystine with various amino acid esters in ethyl acetate to produce unsymmetric cystine peptides.
