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Article
Cellular origin of prognostic chromosomal aberrations in AML patients
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Article
TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia
Members of the TALE (three-amino-acid loop extension) family of atypical homeodomain-containing transcription factors are important downstream effectors of oncogenic fusion proteins involving the mixed lineage...
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Article
Open AccessOncogenic fusion proteins expressed in immature hematopoietic cells fail to recapitulate the transcriptional changes observed in human AML
Reciprocal chromosomal translocations are observed in one-third of acute myeloid leukemia (AML) cases. Targeting and understanding the effects of the resulting aberrant oncogenic fusion proteins may help devel...