Lymphocyte Hybridomas
Second Workshop on “Functional Properties of Tumors of T and B Lymphocytes”
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Article
Monoclonal antibodies and immobilized antibodies
Antibodies in both their free and immobilized state have been the object of considerable industrial and academic interest. A variety of methods are used for preparing and immobilizing antibodies. Applications ...
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Chapter
Injector design for minimum grass sward damage
The effects of slurry injector leg rake angle have been investigated and show reductions of sward damage with increasing angle. The introduction of press wheels immediately after slurry injection has shown sig...
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Chapter and Conference Paper
Multiparameter Approaches to FACS Analysis of Human Leucocyte Cell Surface Antigens
Analysis and definition of cell types involved in regulating and mediating immune reactions has been achieved predominantly through the ability to define specific cell surface components whose expression is re...
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Book and Conference Proceedings
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Article
Natural cytotoxicity of haemopoietic cell populations against murine lymphoid tumours
Homozygous nude and normal mice of 3 strains, BALB/c, CBA and C57BL, were used as sources of nucleated haemopoietic "natural killer" (NK) cells. These killer cells could lyse a wide range of syngeneic and allo...
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Article
In vitro induction of tumour-specific immunity V. Detection of common antigenic determinatnts of murine fibrosarcomas
Two 3-methylcholanthrene and a spontaneous BALB/c fibrosarcoma were examined for tumour-associated antigens (TAA) by in vivo and in vitro induction of tumour-immune responses. When BALB/c mice were immunized to t...
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Chapter
Neoplasms of Immunoglobulin-Producing Cells in Mice
Although murine lymphoid tumors have been extensively used in experimental tumor research for many decades, their use has principally been related to virologic aspects and to studies of tumor immunity. In rece...
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Chapter
Differentiation and Ontogeny of Lymphoid Cells
For many years it has been recognised that lymphocytes play a central role in the initiation and development of both cellular and humoral immunity. In considering the heterogeneous nature of specific immune re...
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Article
Lymphocyte activation in vitro to murine onco-foetal antigens
ONCO-FOETAL antigens (OFAs) are operationally defined as immunogenic cell surface components present on various types of malignant and foetal cells, but not present on adult cells1,2. As OFAs also seem to be shed...
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Article
Growth of B lymphocyte colonies in vitro from mouse lymphoid organs
TECHNIQUES now exist for obtaining clonal growth in semi-solid agar of mouse neutrophil, macrophage, eosinophil, erythropoietic and megakaryocytic colonies1–5. Previous attempts to obtain colony formation by mous...
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Article
Carcinoembryonic Antigen in Whole Serum
A microradioimmunoassay technique is described for detecting carcinoembryonic antigen (CEA) in whole serum. It differs from previous methods in being performed on 0·025 ml of whole serum instead of 5 ml of ser...
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Article
Breakdown of Polyvalent Tolerance in the Chicken by Thymic Grafts
POLYVALENT immunological tolerance of varying degrees to histocompatibility antigens can be induced in non-inbred recipients by the neonatal injection of pooled cells from a wide range of donors. This was demo...
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Article
Effect of Neonatal Thymectomy on the Immune Response in the Chicken
THE function of the mammalian thymus has recently become a matter of considerable interest in the field of immunology. It is now reasonably clear that the presence of the neonatal thymus is essential if the an...
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Article
Immunological Function of Thymus and Bursa of Fabricius: Dissociation of Immunological Responsiveness in Fowls with a Hormonally Arrested Development of Lymphoid Tissues
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Article
Large Lymphocytes and the Simonsen Phenomenon
WHEN blood cells from an adult fowl are inoculated on the chorioallantoic membrane of the 12-day-chick embryo, easily visible opaque foci are produced1,2. This reaction is thought to be similar to the induction o...
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Article
Assay of Corticosteroids in the Chick Embryo
FOR some time we have been studying various manifestations of the reaction induced in chick embryos by the inoculation of leucocytes from normal fowls (the Simonsen phenomenon) with special interest in the pro...
