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  1. No Access

    Article

    Risk of aphakic glaucoma after pars plana-lensectomy with and without removal of the peripheral lens capsule

    The etiology of aphakic glaucoma is unclear. It has been suggested that remaining lens epithelium releases cytokines transducing trabecular meshwork cells. Therefore, we compared two cohorts of children underg...

    M. Stech, B. Grundel, M. Daniel, D. Böhringer, L. Joachimsen, N. Gross, C. Wolf… in Eye (2019)

  2. No Access

    Article

    Indikation und Technik der transkonjunktivalen Optikusscheidenfensterung

    Das primär chirurgische Vorgehen zur Senkung eines chronisch erhöhten Hirndrucks bei Pseudotumor-cerebri-Syndrom ist ein ventrikulärer Shunt. Wenn jedoch die ophthalmologischen Symptome gegenüber den neurologi...

    Prof. Dr. W. A. Lagrèze FEBO, N. Gross, J. Biermann, L. Joachimsen in Der Ophthalmologe (2017)

  3. No Access

    Article

    Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling

    Head and neck squamous cell carcinoma (HNSCC) patients have a poor prognosis, with invasion and metastasis as major causes of mortality. The phosphatidylinositol 3-kinase (PI3K) pathway regulates a wide range ...

    L Du, X Chen, Y Cao, L Lu, F Zhang, S Bornstein, Y Li, P Owens, S Malkoski… in Oncogene (2016)

  4. No Access

    Article

    RNA interference screening identifies a novel role for autocrine fibroblast growth factor signaling in neuroblastoma chemoresistance

    Chemotherapeutic drug resistance is one of the major causes for treatment failure in high-risk neuroblastoma (NB), the most common extra cranial solid tumor in children. Poor prognosis is typically associated ...

    F Salm, P Cwiek, A Ghosal, A Lucia Buccarello, F Largey, C Wotzkow, K Höland… in Oncogene (2013)

  5. No Access

    Article

    The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/β-catenin pathway

    The development of chemoresistance represents a major obstacle in the successful treatment of cancers such as neuroblastoma (NB), a particularly aggressive childhood solid tumour. The mechanisms underlying the...

    M Flahaut, R Meier, A Coulon, K A Nardou, F K Niggli, D Martinet, J S Beckmann… in Oncogene (2009)

  6. No Access

    Article

    Fungal prophylaxis by reduction of fungal colonization by oral administration of bovine anti-Candida antibodies in bone marrow transplant recipients

    Candida overgrowth and invasion constitute a serious threat with a high mortality in BMT recipients. Currently available topical antifungal prophylaxis is largely ineffective, and as resistance to existing, ab...

    J Tollemar, N Gross, N Dolgiras, C Jarstrand, O Ringdén… in Bone Marrow Transplantation (1999)

  7. No Access

    Article

    Immunocytochemical detection of neuroblastoma cells infiltrating clinical bone marrow samples

    To evaluate the feasibility and clinical usefulness of immunocytochemical detection of bone marrow metastases in neuroblastoma, we studied bone marrow samples from patients undergoing intensive therapy, follow...

    D. Beck, O. Maritaz, N. Gross, M. Favrot, N. Vultier… in European Journal of Pediatrics (1988)