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    Article

    Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling

    Head and neck squamous cell carcinoma (HNSCC) patients have a poor prognosis, with invasion and metastasis as major causes of mortality. The phosphatidylinositol 3-kinase (PI3K) pathway regulates a wide range ...

    L Du, X Chen, Y Cao, L Lu, F Zhang, S Bornstein, Y Li, P Owens, S Malkoski in Oncogene (2016)

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    Article

    Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1

    C-terminal binding protein 1 (CtBP1) is a transcriptional co-repressor and metabolic sensory protein, which often represses tumor suppressor genes. Hence, we sought to determine if CtBP1 affects expression of ...

    Y Deng, J Liu, G Han, S-L Lu, S-Y Wang, S Malkoski, A C Tan, C Deng, X-J Wang in Oncogene (2010)

  3. Article

    The biphasic aPTT waveform to diagnose sepsis in patients with systemic inflammatory response syndrome

    D Hagg, S Malkoski, C Phillips, D Nichols, D Jacoby in Critical Care (2007)