11 Result(s)
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Muthukumar Thangavelu
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Article
Open AccessBioengineered corneal tissue for minimally invasive vision restoration in advanced keratoconus in two clinical cohorts
Visual impairment from corneal stromal disease affects millions worldwide. We describe a cell-free engineered corneal tissue, bioengineered porcine construct, double crosslinked (BPCDX) and a minimally invasiv...
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Article
Isolation and screening of potassium solubilizing bacteria from saxicolous habitat and their impact on tomato growth in different soil types
Bacteria that solubilize nutrients in the soil are commonly used as bio-inoculants for promoting the growth of different crop species. However, the influence of potassium (K) solubilizing bacteria (KSB) origin...
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Article
Open AccessA porous collagen-based hydrogel and implantation method for corneal stromal regeneration and sustained local drug delivery
Biomaterials designed to replace the diseased cornea could be used to treat corneal blindness where human donor tissue is in short supply, but challenges are the integration of biomaterials with host tissue an...
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Article
Interactive Influence of Soil and Plant Genotypes on Mycorrhizal Dependency in Finger Millet
The present study aims to assess the impact of soil types (Alfisol and Vertisol) on mycorrhizal dependency and nutrient acquisition in ten genotypes of finger millet (Eleusine coracana L.Gaertn.) (GPU 28, GPU 45,...
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Article
Fabrication of POX/PLGA Scaffold for the Potential Application of Tissue Engineering and Cell Transplantation
Poly lactic-co-glycolic acid (PLGA), a synthetic polymer, belongs to the fabrication of poly(α-hydroxy acid) systems approved by the US Food and Drug Administration. PLGA has been widely used in clinical appli...
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Bone Regeneration Using Duck’s Feet-Derived Collagen Scaffold as an Alternative Collagen Source
Collagen is an important component that makes 25–35% of our body proteins. Over the past decades, tissue engineers have been designing collagen-based biocompatible materials and studying their applications in ...
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Chapter
Enhancing Osteochondral Tissue Regeneration of Gellan Gum by Incorporating Gallus gallus var Domesticus-Derived Demineralized Bone Particle
Treatment for the osteochondral defects (ODs) is more challenging nowadays that needs to be addressed by develo** alternative bone tissue engineering materials. Gellan gum (GG) is a widely used natural polys...
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Open AccessRevascularization after angiogenesis inhibition favors new sprouting over abandoned vessel reuse
Inhibiting pathologic angiogenesis can halt disease progression, but such inhibition may offer only a temporary benefit, followed by tissue revascularization after treatment stoppage. This revascularization, h...
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Article
UV-Irradiated RPE Cells Assist Differentiation of Bone Marrow Derived Mesenchymal Stem Cells into RPE Cells Under a Direct Co-Culture Environment
Degeneration of retinal pigment epithelium cells (RPE) or delamination of RPE from Bruch’s membrane causes visual impairment. While regeneration of RPE cells is desirable to treat age-related macular degenerat...
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Article
Morphological Modification of Carbon Nanoparticles after Interacting with Methotrexate as a Potential Anticancer Agent
Production of highly penetrable and targetable drug delivery particles is mainly focused by current therapy and such focus is achieved in our present study. The carbon nanoparticle (CNP) prepared from purely n...
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Open AccessSelective IKK2 inhibitor IMD0354 disrupts NF-κB signaling to suppress corneal inflammation and angiogenesis
Corneal neovascularization is a sight-threatening condition caused by angiogenesis in the normally avascular cornea. Neovascularization of the cornea is often associated with an inflammatory response, thus tar...
