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  1. No Access

    Article

    Reference values of diaphragmatic dimensions in healthy children aged 0–8 years

    Diaphragmatic thickness (Tdi) and diaphragm thickening fraction (dTF) are widely used parameters in ultrasound studies of the diaphragm in mechanically ventilated children, but normal values for healthy childr...

    Anita Duyndam, Joke Smit, Leo Heunks, Jeroen Molinger in European Journal of Pediatrics (2023)

  2. No Access

    Article

    COMFORTneo scale: a reliable and valid instrument to measure prolonged pain in neonates?

    We studied the reliability and validity of the COMFORTneo scale, designed to measure neonatal prolonged pain.

    Naomi J. Meesters, Tinne Dilles, Joost van Rosmalen in Journal of Perinatology (2023)

  3. Article

    Open Access

    Intensive Care Medicine – Paediatric and Neonatal (ICM-PN): creating a journal to fill a gap and strengthen our domain

    Daniele De Luca, Paulien Raymakers in Intensive Care Medicine – Paediatric and … (2023)

  4. No Access

    Article

    Postoperative breakthrough pain in paediatric cardiac surgery not reduced by increased morphine concentrations

    Morphine is commonly used for postoperative analgesia in children. Here we studied the pharmacodynamics of morphine in children after cardiac surgery receiving protocolized morphine.

    Sjoerd de Hoogd, Sebastiaan C. Goulooze, Abraham J. Valkenburg in Pediatric Research (2021)

  5. Article

    Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg/kg intravenous acetaminophen in very-preterm infants

    Exposure to acetaminophen and its metabolites in very-preterm infants is partly unknown. We investigated the exposure to acetaminophen and its metabolites upon 10, 15, or 20 mg/kg intravenous acetaminophen in ...

    Robert B Flint, Daniella W Roofthooft, Anne van Rongen in Pediatric Research (2017)

  6. Article

    Open Access

    Thermal quantitative sensory testing in healthy Dutch children and adolescents standardized test paradigm and Dutch reference values

    Quantitative sensory testing (QST) is often used to measure children’s and adults’ detection- and pain thresholds in a quantitative manner. In children especially the Thermal Sensory Analyzer (TSA-II) is often...

    Gerbrich E. van den Bosch, Monique van Dijk, Dick Tibboel in BMC Pediatrics (2017)

  7. Article

    Open Access

    Clinical recommendations for pain, sedation, withdrawal and delirium assessment in critically ill infants and children: an ESPNIC position statement for healthcare professionals

    This position statement provides clinical recommendations for the assessment of pain, level of sedation, iatrogenic withdrawal syndrome and delirium in critically ill infants and children. Admission to a neona...

    Julia Harris, Anne-Sylvie Ramelet, Monique van Dijk in Intensive Care Medicine (2016)

  8. Article

    Open Access

    Limited effects of intravenous paracetamol on patent ductus arteriosus in very low birth weight infants with contraindications for ibuprofen or after ibuprofen failure

    Finding the optimal pharmacological treatment of a patent ductus arteriosus (PDA) in preterm neonates remains challenging. There is a growing interest in paracetamol as a new drug for PDA closure. In this pros...

    Daniëlla W. E. Roofthooft, Ingrid M. van Beynum in European Journal of Pediatrics (2015)

  9. Article

    Open Access

    Pain in Intellectually Disabled Children: Towards Evidence-Based Pharmacotherapy?

    This critical opinion article deals with the challenges of finding the most effective pharmacotherapeutic options for the management of pain in intellectually disabled children and provides recommendations for...

    Abraham J. Valkenburg, Tom G. de Leeuw, Monique van Dijk, Dick Tibboel in Pediatric Drugs (2015)

  10. Article

    Paediatric critical incident analysis: lessons learnt on analysis, recommendations and implementation

    The objectives of this study were to identify causal and contributing factors of serious patient safety incidents in a paediatric university hospital, to report on ensuing recommendations and to assess the ext...

    Cynthia van der Starre, Monique van Dijk, Ada van den Bos in European Journal of Pediatrics (2014)

  11. Article

    Optimal sedation in pediatric intensive care patients: a systematic review

    Sedatives administered to critically ill children should be titrated to effect, because both under- and oversedation may have negative effects. We conducted a systematic review to examine reported incidences o...

    Nienke J. Vet, Erwin Ista, Saskia N. de Wildt, Monique van Dijk in Intensive Care Medicine (2013)

  12. No Access

    Article

    Functional MRI pain studies in children? Yes, we (s)can!

    Gerbrich E. van den Bosch, Tonya White, Dick Tibboel in Pediatric Radiology (2013)

  13. Article

    Skin conductance peaks could result from changes in vital parameters unrelated to pain

    Pain is usually assessed by the interpretation of behavior, which can be subjective. Therefore, there is an ongoing search for more objective methods. Performance of skin conductance measurement as a pain asse...

    Abraham J. Valkenburg, Sjoerd P. Niehof, Monique van Dijk in Pediatric Research (2012)

  14. Article

    Open Access

    Real-time registration of adverse events in Dutch hospitalized children in general pediatric units: first experiences

    The objectives of this study are to describe the number and nature of adverse events occurring in general pediatric practice, to describe factors contributing to the occurrence of these adverse events, and to ...

    Cynthia van der Starre, Monique van Dijk, Dick Tibboel in European Journal of Pediatrics (2012)

  15. Article

    Open Access

    Screening pediatric delirium with an adapted version of the Sophia Observation withdrawal Symptoms scale (SOS)

    Monique van Dijk, Hennie Knoester, Babette S. van Beusekom in Intensive Care Medicine (2012)

  16. Article

    Open Access

    Construction of the Sophia Observation withdrawal Symptoms-scale (SOS) for critically ill children

    To construct a reliable and clinically practical instrument for monitoring opioids and benzodiazepine withdrawal symptoms in pediatric ICU patients.

    Erwin Ista, Monique van Dijk, Matthijs de Hoog, Dick Tibboel in Intensive Care Medicine (2009)

  17. Article

    Withdrawal symptoms in children after long-term administration of sedatives and/or analgesics: a literature review. “Assessment remains troublesome”

    Prolonged administration of benzodiazepines and/or opioids to children in a pediatric intensive care unit (PICU) may induce physiological dependence and withdrawal symptoms.

    Erwin Ista, Monique van Dijk, Claudia Gamel, Dick Tibboel in Intensive Care Medicine (2007)

  18. No Access

    Article

    Sedation and analgesia in the PICU: many questions remain

    Sandra Prins, Monique van Dijk, Dick Tibboel in Intensive Care Medicine (2006)

  19. No Access

    Article

    Postoperative pain in the neonate: age-related differences in morphine requirements and metabolism

    To investigate age-related differences in morphine requirements and metabolism in full-term neonates.

    Nancy J. Bouwmeester, Wim C. J. Hop, Monique van Dijk in Intensive Care Medicine (2003)