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Article
Open AccessNovel 9-(alkylthio)-Acenaphtho[1,2-e]-1,2,4-triazine derivatives: synthesis, cytotoxic activity and molecular docking studies on B-cell lymphoma 2 (Bcl-2)
Acenaphtho derivatives have been reported as antitumor agents. Due to this fact and also with the aim of develo** the chemistry of potentially bioactive heterocyclic compounds via efficient reactions, a faci...
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Article
QM study and conformational analysis of an isatin Schiff base as a potential cytotoxic agent
Isatin is an important compound from the biological aspect of view. It is an endogenous substance and moreover; various pharmacological activities have been reported for isatin and its derivatives. In-vitro cy...
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Article
Synthesis, biological activity and docking study of some new isatin Schiff base derivatives
A set of novel Schiff bases of isatin were synthesized and characterized by reaction of isatin with various aromatic or heterocyclic primary amines. Cytotoxic activities for some of the synthesized compounds w...