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Article
Open AccessCurrent status of the surgical training system in Japan: results of a nationwide questionnaire survey of graduating surgical trainees
To identify the problems trainees face during surgical training in Japan.
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Article
Glycosylation profiles of breast cancer cells may represent clonal variations of multiple organ metastases
Glycosylation changes of cancer cells are known to be associated with malignant progression and metastases and potentially determine the organ-selective nature of metastasis as theorized by Paget (Lancet 1:571...
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Article
Open Access2023 updated MASCC/ESMO consensus recommendations: prevention of nausea and vomiting following multiple-day chemotherapy, high-dose chemotherapy, and breakthrough nausea and vomiting
This review is an update of the MASCC/ESMO 2015 recommendations for the prophylaxis of acute and delayed nausea and vomiting induced by multiple-day chemotherapy, high-dose chemotherapy, and breakthrough nause...
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Article
The degree of satisfaction and level of learning in male and female surgical residents: a nationwide questionnaire survey of graduating residents in Japan
Since 2002, the Japan Surgical Society has established a board certification system for surgeons to be certified for a specialty. Surgery remains a male-dominated field in Japan. This study aimed to clarify if...
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Article
Open AccessPossible correlation of apical localization of MUC1 glycoprotein with luminal A-like status of breast cancer
Adjuvant chemotherapy has played a major role in the treatment of hormone receptor-positive breast cancer for many years. To better determine which patient subsets need adjuvant chemotherapy, various gene expr...
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Article
Open AccessAcute myocarditis during adjuvant therapies for breast cancer: a case report
With the improvement of optimal perioperative drug therapy for breast cancer patients, physicians now have to treat the adverse effects and comorbidities associated with long-term treatments. We report a case ...
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Article
Absolute lymphocyte count decreases with disease progression and is a potential prognostic marker for metastatic breast cancer
Peripheral blood parameters such as the neutrophil-to-lymphocyte ratio (NLR) are prognostic markers for breast cancer patients. For instance, patients with a high NLR have a poor prognosis. Meanwhile, high abs...
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Article
Open AccessHigh platelet-to-lymphocyte ratios in triple-negative breast cancer associates with immunosuppressive status of TILs
Rating lymphocytes (TILs) are a prognostic marker in breast cancer and high TIL infiltration correlates with better patient outcomes. Meanwhile, parameters involving immune cells in peripheral blood have also ...
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Article
Open AccessSuccessful treatment with steroid pulse therapy for a COVID-19 case with progressive respiratory failure during treatment for pleural metastasis of breast cancer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients are at high risk for develo** severe conditions if other comorbidities are present, such as advanced cancer. Although the regula...
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Open AccessComparison of tumors with HER2 overexpression versus HER2 amplification in HER2-positive breast cancer patients
Human epidermal growth factor receptor 2 (HER2)-positive tumors are defined by protein overexpression (3+) or gene amplification using immunohistochemistry (IHC) or fluorescence in situ hybridization (FISH), resp...
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Open AccessDepressive and anxiety symptoms among Japanese cancer survivors: Japan cancer survivorship research project
This study aimed to clarify predictors of depressive symptoms and anxiety symptoms after cancer diagnosis among Japanese cancer survivors (CSs).
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Article
Open AccessDrug-induced aortitis of the subclavian artery caused by pegfilgrastim: a case report
Pegfilgrastim is a modified version of granulocyte-colony stimulating factor (G-CSF), with a polyethylene glycol (PEG) that prolongs its half-life in peripheral blood. It is prophylactically administered durin...
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Open AccessMetastatic breast tumors from extramammary malignancies: a case series
Metastatic breast tumors from extramammary malignancies are quite rare. Characteristics of such tumors are unclear due to small number of reported cases. During 2012–2019, approximately 3,500 malignant breast ...
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Article
Open AccessCerebral hemorrhage due to amyloid angiopathy that was difficult to differentiate from breast cancer metastasis: a case report
Breast cancer patients are known to develop brain metastasis at a relatively high frequency. However, imaging findings of brain metastases vary, and it is sometimes very difficult to distinguish these from oth...
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Open AccessPredictors of resignation and sick leave after cancer diagnosis among Japanese breast cancer survivors: a cross-sectional study
In Japan, 55.5% of breast cancer survivors (BCSs) are of working age, so various perspectives regarding return to work (RTW) after cancer diagnosis need to be considered. Therefore, this study aimed to clarify...
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Article
Ipsilateral breast tumor control following hypofractionated and conventional fractionated whole-breast irradiation for early breast cancer: a long-term follow-up
Long-term follow-up of Japanese women with breast cancer who underwent hypofractionated whole-breast irradiation (HF-WBI) has not been well documented. Therefore, we compared the treatment results of HF-WBI an...
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Article
Is there disparity between regions and facilities in surgical resident training in Japan? Insights from a national survey
This study sought to assess the disparity between regions and facilities in surgical resident training in Japan via a national level needs-assessment.
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Article
Are graduating residents sufficiently competent? Results of a national gap analysis survey of program directors and graduating residents in Japan
To evaluate the self-assessed competency of graduating residents (GRs) in Japan upon completion of their residency and to identify the gap between their competency and the competency expected by their program ...
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Article
High FOXA1 protein expression might predict late recurrence in patients with estrogen-positive and HER2-negative breast cancer
Multi-gene expression assays have been developed with the aim of predicting late recurrence in patients with estrogen receptor (ER)-positive breast cancer. However, establishment of alternative markers based ...
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Article
Neutrophil-to-lymphocyte ratio and histological type might predict clinical responses to eriburin-based treatment in patients with metastatic breast cancer
Metastatic breast cancer (MBC) is generally considered to be incurable. Although many options are available for treating MBC, physicians often encounter difficulties in choosing the most appropriate treatment ...
