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Article
Open AccessSuccessful treatment of acute tubulointerstitial nephritis probably due to Benikoji CholesteHelp®, a supplement containing red yeast rice
Red yeast rice has been used to produce alcoholic beverages and various fermented foods especially in East Asia. Since around March 2024, there have been many cases of kidney dysfunction in people who have tak...
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Article
Glycosylation profiles of breast cancer cells may represent clonal variations of multiple organ metastases
Glycosylation changes of cancer cells are known to be associated with malignant progression and metastases and potentially determine the organ-selective nature of metastasis as theorized by Paget (Lancet 1:571...
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Article
Open AccessHigh platelet-to-lymphocyte ratios in triple-negative breast cancer associates with immunosuppressive status of TILs
Rating lymphocytes (TILs) are a prognostic marker in breast cancer and high TIL infiltration correlates with better patient outcomes. Meanwhile, parameters involving immune cells in peripheral blood have also ...
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Article
CRYβB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer
Expression of β-crystallin B2 (CRYβB2) is elevated in African American (AA) breast tumors. The underlying mechanisms of CRYβB2-induced malignancy and the association of CRYβB2 protein expression with survival ...
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Article
Open AccessA case of simultaneous abdominal wall metastasis of hepatocellular carcinoma with long-term relapse-free survival after laparoscopic resection
We report our experience of an extremely rare case of a simultaneous extrahepatic metastasis of hepatocellular carcinoma (HCC) with long-term relapse-free survival, treated by laparoscopic resection of an abdo...
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Article
High FOXA1 protein expression might predict late recurrence in patients with estrogen-positive and HER2-negative breast cancer
Multi-gene expression assays have been developed with the aim of predicting late recurrence in patients with estrogen receptor (ER)-positive breast cancer. However, establishment of alternative markers based ...
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Pathology of Lynch Syndrome-Associated Tumors
Lynch syndrome is caused by the DNA mismatch repair (MMR) genes, MLH1, MSH2, PMS2, MSH6, and EPCAM. Though the proteins encoded by these genes are stained by immunohistochemistry, and loss of the proteins can ...
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Article
Cotyledonoid dissecting leiomyoma of the uterus: report of two cases
Cotyledonoid dissecting leiomyoma (Sternberg tumor) is a rare variant of the uterine smooth muscle tumor. Although this tumor is a benign tumor clinically and pathologically, the appearance and growth pattern ...