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  1. Article

    Open Access

    Successful treatment of acute tubulointerstitial nephritis probably due to Benikoji CholesteHelp®, a supplement containing red yeast rice

    Red yeast rice has been used to produce alcoholic beverages and various fermented foods especially in East Asia. Since around March 2024, there have been many cases of kidney dysfunction in people who have tak...

    Masayuki Maiguma, Masao Kihara, Maki Hamaguchi, Takashi Kobayashi in CEN Case Reports (2024)

  2. No Access

    Article

    Glycosylation profiles of breast cancer cells may represent clonal variations of multiple organ metastases

    Glycosylation changes of cancer cells are known to be associated with malignant progression and metastases and potentially determine the organ-selective nature of metastasis as theorized by Paget (Lancet 1:571...

    Yoshiya Horimoto, May Thinzar Hlaing, Harumi Saeki in Clinical & Experimental Metastasis (2024)

  3. Article

    Open Access

    High platelet-to-lymphocyte ratios in triple-negative breast cancer associates with immunosuppressive status of TILs

    Rating lymphocytes (TILs) are a prognostic marker in breast cancer and high TIL infiltration correlates with better patient outcomes. Meanwhile, parameters involving immune cells in peripheral blood have also ...

    Hiroko Onagi, Yoshiya Horimoto, Asumi Sakaguchi, Daiki Ikarashi in Breast Cancer Research (2022)

  4. No Access

    Article

    CRYβB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer

    Expression of β-crystallin B2 (CRYβB2) is elevated in African American (AA) breast tumors. The underlying mechanisms of CRYβB2-induced malignancy and the association of CRYβB2 protein expression with survival ...

    Yu Yan, Athira Narayan, Soonweng Cho, Zhiqiang Cheng, Jun O. Liu, Heng Zhu in Oncogene (2021)

  5. Article

    Open Access

    A case of simultaneous abdominal wall metastasis of hepatocellular carcinoma with long-term relapse-free survival after laparoscopic resection

    We report our experience of an extremely rare case of a simultaneous extrahepatic metastasis of hepatocellular carcinoma (HCC) with long-term relapse-free survival, treated by laparoscopic resection of an abdo...

    Michitoshi Goto, Kazuhiro Sakamoto in International Cancer Conference Journal (2021)

  6. No Access

    Article

    High FOXA1 protein expression might predict late recurrence in patients with estrogen-positive and HER2-negative breast cancer

    Multi-gene expression assays have been developed with the aim of predicting late recurrence in patients with estrogen receptor (ER)-positive breast cancer. However, establishment of alternative markers based ...

    Yoshiya Horimoto, Noriko Sasahara, Ritsuko Sasaki in Breast Cancer Research and Treatment (2020)

  7. No Access

    Chapter

    Pathology of Lynch Syndrome-Associated Tumors

    Lynch syndrome is caused by the DNA mismatch repair (MMR) genes, MLH1, MSH2, PMS2, MSH6, and EPCAM. Though the proteins encoded by these genes are stained by immunohistochemistry, and loss of the proteins can ...

    Harumi Saeki, Okio Hino in Lynch Syndrome (2020)

  8. No Access

    Article

    Cotyledonoid dissecting leiomyoma of the uterus: report of two cases

    Cotyledonoid dissecting leiomyoma (Sternberg tumor) is a rare variant of the uterine smooth muscle tumor. Although this tumor is a benign tumor clinically and pathologically, the appearance and growth pattern ...

    Harumi Saeki, Chikako Suzuki, Shigetaka Yamasaki in Archives of Gynecology and Obstetrics (2015)