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  1. No Access

    Article

    mEosEM withstands osmium staining and Epon embedding for super-resolution CLEM

    Super-resolution correlative light and electron microscopy (SR-CLEM) is a powerful approach for imaging specific molecules at the nanoscale in the context of the cellular ultrastructure. Epon epoxy resin embed...

    Zhifei Fu, Dingming Peng, Mingshu Zhang, Fudong Xue, Rui Zhang… in Nature Methods (2020)

  2. No Access

    Article

    Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming

    Crystallographic and functional studies reveal the arch-shaped architecture of the Munc13 MUN domain and show the molecular basis for Munc13's role in synaptic-vesicle priming by mediating syntaxin-1 opening a...

    **aoyu Yang, Shen Wang, Yi Sheng, Mingshu Zhang… in Nature Structural & Molecular Biology (2015)

  3. No Access

    Article

    Rational design of true monomeric and bright photoactivatable fluorescent proteins

    Structure determination followed by targeted engineering of the popular photoactivatable fluorescent protein monomeric (m)Eos2 yields mEos3 versions that are more monomeric and less disruptive in protein fusio...

    Mingshu Zhang, Hao Chang, Yongdeng Zhang, Junwei Yu, Lijie Wu, Wei Ji… in Nature Methods (2012)