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    Article

    mEosEM withstands osmium staining and Epon embedding for super-resolution CLEM

    Super-resolution correlative light and electron microscopy (SR-CLEM) is a powerful approach for imaging specific molecules at the nanoscale in the context of the cellular ultrastructure. Epon epoxy resin embed...

    Zhifei Fu, Dingming Peng, Mingshu Zhang, Fudong Xue, Rui Zhang in Nature Methods (2020)

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    Open Access

    Drift correction for single-molecule imaging by molecular constraint field, a distance minimum metric

    The recent developments of far-field optical microscopy (single molecule imaging techniques) have overcome the diffraction barrier of light and improve image resolution by a factor of ten compared with convent...

    Renmin Han, Liansan Wang, Fan Xu, Yongdeng Zhang, Mingshu Zhang in BMC Biophysics (2015)

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    Article

    Rational design of true monomeric and bright photoactivatable fluorescent proteins

    Structure determination followed by targeted engineering of the popular photoactivatable fluorescent protein monomeric (m)Eos2 yields mEos3 versions that are more monomeric and less disruptive in protein fusio...

    Mingshu Zhang, Hao Chang, Yongdeng Zhang, Junwei Yu, Lijie Wu, Wei Ji in Nature Methods (2012)