-
Article
Open AccessHepatitis B virus infection among pregnant mothers and children after the introduction of the universal vaccination program in Central Vietnam
A birth cohort study was conducted in Khan Hoa Province, central Vietnam between 2009 and 2012 to determine the seroprevalence of hepatitis B virus (HBV) in pregnant women and their children, and associated ri...
-
Article
Open AccessCorrection to: Changes in nutritional status of children who lived in temporary shelters in Bhaktapur municipality after the 2015 Nepal earthquake
An amendment to this paper has been published and can be accessed via the original article.
-
Article
Open AccessChanges in nutritional status of children who lived in temporary shelters in Bhaktapur municipality after the 2015 Nepal earthquake
The nutritional status of children may deteriorate after natural disasters such as earthquakes. A 7.8 Richter scale earthquake struck Nepal in 2015 that affected 1.1 million children. Children whose homes were...
-
Article
Open AccessAuthor Correction: Exposure to paternal tobacco smoking increased child hospitalization for lower respiratory infections but not for other diseases in Vietnam
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
-
Article
Open AccessAsthma, Rhinoconjunctivitis, Eczema, and the Association with Perinatal Anthropometric Factors in Vietnamese Children
Few studies have investigated possible causative and protective factors associated with allergic diseases in resource-limited countries, Southeast Asia. We estimated the current prevalence of asthma, rhinoconj...
-
Article
Open AccessRecycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region
CD133 is a transmembranous protein that mainly localises to the plasma membrane in haematopoietic and neural stem cells as well as cancer stem cells. Although CD133 also localises to the cytoplasm, the mechani...
-
Article
Open AccessEffects of HLA-DRB1 alleles on susceptibility and clinical manifestations in Japanese patients with adult onset Still’s disease
HLA-DRB1 alleles are major determinants of genetic predisposition to rheumatic diseases. We assessed whether DRB1 alleles are associated with susceptibility to particular clinical feat...
-
Article
Open AccessPrincipal contribution of HLA-DQ alleles, DQB1*06:04 and DQB1*03:01, to disease resistance against primary biliary cholangitis in a Japanese population
Identification of the primary allele(s) in HLA class II associated diseases remains challenging because of a tight linkage between alleles of HLA-DR and -DQ loci. In the present study, we determined the genotypes...
-
Article
Open AccessIdentification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis
Numerous genome-wide association studies (GWAS) have been performed to identify susceptibility genes to various human complex diseases. However, in many cases, neither a functional variant nor a disease suscep...
-
Article
Open AccessExposure to paternal tobacco smoking increased child hospitalization for lower respiratory infections but not for other diseases in Vietnam
Exposure to environmental tobacco smoke (ETS) is an important modifiable risk factor for child hospitalization, although its contribution is not well documented in countries where ETS due to maternal tobacco s...
-
Article
Open AccessFamilial Mediterranean fever is no longer a rare disease in Japan
The aim of this study was to evaluate the clinical manifestations and prevalence of familial Mediterranean fever (FMF) in Japanese patients with unexplained fever and rheumatic manifestations.
-
Article
Open AccessLack of association between the CARD10 rs6000782 polymorphism and type 1 autoimmune hepatitis in a Japanese population
Previous genome-wide association studies have evaluated the impact of common genetic variants and identified several non-HLA risk loci associated with autoimmune liver diseases. More recent genome-wide associa...
-
Article
Coexistence of familial Mediterranean fever and rheumatoid arthritis
Familial Mediterranean fever (FMF) is an autoinflammatory disorder characterized by recurrent febrile polyserositis and arthritis. Although accompanying seronegative spondyloarthropathy has been reported in FM...
-
Article
Open AccessToll-like receptor 9 (TLR9) polymorphism associated with symptomatic malaria: a cohort study
In areas mesoendemic for malaria transmission, symptomatic individuals play a significant role as reservoirs for malaria infection. Understanding the pathogenesis of symptomatic malaria is important in devisin...
-
Article
Positive selection of Toll-like receptor 2 polymorphisms in two closely related old world monkey species, rhesus and Japanese macaques
Toll-like receptor 2 (TLR2) plays an important role in the recognition of a variety of pathogenic microbes. In the present study, we compared polymorphisms of TLR2 locus in two closely related old world monkey sp...
-
Article
Histopathological studies in two strains of semi-immune mice infected with Plasmodium berghei ANKA after chronic exposure
To mimic a human malaria infection in the endemic condition, two strains of mice (Balb/c and CBA) were infected and treated several times to generate so-called semi-immune status. As previously reported, neith...
-
Article
Open AccessPartial mitochondrial DNA sequences suggest the existence of a cryptic species within the Leucosphyrus group of the genus Anopheles (Diptera: Culicidae), forest malaria vectors, in northern Vietnam
During the last decade, Southeast Asian countries have been very successful in reducing the burden of malaria. However, malaria remains endemic in these countries, especially in remote and forested areas. The ...
-
Article
Megakaryoblastic leukemia factor-1 gene in the susceptibility to coronary artery disease
Coronary artery disease (CAD) is based on the atherosclerosis of coronary artery and may manifest with myocardial infarction or angina pectoris. Although it is widely accepted that genetic factors are linked t...
-
Article
Open AccessRate of red blood cell destruction varies in different strains of mice infected with Plasmodium berghei-ANKA after chronic exposure
Severe malaria anaemia in the semi-immune individuals in the holo-endemic area has been observed to occur at low parasite density with individual variation in the responses. Thus the following has been thought...
-
Article
Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations
Coronary artery disease (CAD) has become a major health problem in many countries. Recent genome-wide association studies have identified the association between rs1333049 on chromosome 9p21 and susceptibility...
