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Article
Open AccessAuthor Correction: Annual phenology and migration routes to breeding grounds in western-central North Pacific sei whales
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Article
Open AccessAnnual phenology and migration routes to breeding grounds in western-central North Pacific sei whales
The sei whale (Balaenoptera borealis) is an important species among baleen whales in the North Pacific and plays a significant role in the ecosystem. Despite the importance of this species, information regarding ...
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Article
Open AccessRight to left ventricular volume ratio is associated with mortality in congenital diaphragmatic hernia
Congenital diaphragmatic hernia (CDH) is associated with high neonatal mortality. We performed this study to test the hypothesis that left ventricular (LV) and right ventricular (RV) volumes assessed by three-...
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Article
Open AccessSerious hazards of transfusion: evaluating the dangers of a wrong patient autologous salvaged blood in cardiac surgery
The past half century has seen the near eradication of transfusion-associated hazards. Intraoperative cell salvage while widely used still poses significant risks and hazards due to human error. We report on a...
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Article
Open AccessBroadband coherent Raman spectroscopy running at 24,000 spectra per second
We present a Fourier-transform coherent anti-Stokes Raman scattering (FT-CARS) spectroscopy technique that achieves broadband CARS measurements at an ultrahigh scan rate of more than 20,000 spectra/s – more th...
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Article
Open AccessStudy of Sustained Blood Pressure-Lowering Effect of Azelnidipine Guided by Self-Measured Morning and Evening Home Blood Pressure: Subgroup Analysis of the At-HOME Study
Morning hypertension is a risk factor for cardiovascular and cerebrovascular events, and consequently diagnosis and control of morning hypertension are considered very important. We previously reported the res...
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Article
Open AccessInhibitory Effects of Azelnidipine Tablets on Morning Hypertension
Morning hypertension is a risk factor for cardiovascular and cerebrovascular events. Furthermore, it is a useful measure for definitive diagnosis of hypertension, and patients who self-assess their own blood p...
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Chapter and Conference Paper
Development and Evaluation of a Historical Tour Support System Using 3D Graphics and Mobile Terminal
We have developed a historical tour support system based on Matsue Castle and the surrounding historic area. The system has pre tour mode using 3D graphics and tour mode using a mobile terminal. We used Virtoo...
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Article
Megakaryoblastic leukemia factor-1 gene in the susceptibility to coronary artery disease
Coronary artery disease (CAD) is based on the atherosclerosis of coronary artery and may manifest with myocardial infarction or angina pectoris. Although it is widely accepted that genetic factors are linked t...
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Article
Open AccessA possible mechanism of intravesical BCG therapy for human bladder carcinoma: involvement of innate effector cells for the inhibition of tumor growth
Intravesical bacillus Calmette-Guerin (BCG) therapy is considered the most successful immunotherapy against solid tumors of human bladder carcinoma. To determine the actual effector cells activated by intraves...
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Article
Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations
Coronary artery disease (CAD) has become a major health problem in many countries. Recent genome-wide association studies have identified the association between rs1333049 on chromosome 9p21 and susceptibility...
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Article
Synergistic contribution of CD14 and HLA loci in the susceptibility to Buerger disease
Buerger disease (BD) is an occulusive vascular disease of unknown etiology. Although cigarette smoking is a well-known risk factor of BD, genetic factors may also play a role in the etiology. Because chronic b...
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Article
Functional analysis of titin/connectin N2-B mutations found in cardiomyopathy
Hypertrophic cardiomyopathy and dilated cardiomyopathy are two major clinical phenotypes of “idiopathic” cardiomyopathy. Recent molecular genetic analyses have now revealed that “idiopathic” cardiomyopathy is ...
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Article
A Young Japanese Man With Relentless Placoid Chorioretinitis
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Chapter
Mutational Profiles and Molecular Etiologies of Hypertrophic Cardiomyopathy and Dilated Cardiomyopathy in Asian Populations
Idiopathic cardiomyopathy (ICM) had been defined as the cardiac disease of unknown etiology. There are two major clinical phenotypes of ICM; hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM). ...
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Article
Characterization of the human nebulette gene: a polymorphism in an actin-binding motif is associated with nonfamilial idiopathic dilated cardiomyopathy
Idiopathic dilated cardiomyopathy (IDC) is characterized by a thin-walled heart with systolic dysfunction of unknown etiology. Because abnormalities in genes for cytoskeletal proteins related to Z-disc functi...
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Article
Participation of Bcl-2/Bax-α in Glutamate-induced Apoptosis of Human Glioblastoma Cells
Glutamate has been shown to function as a toxic agent in neuronal and glial cells, as well as an excitatory neurotransmitter throughout the central nervous system. In the present study, we examined the effect ...
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Article
P-Glycoprotein-Dependent Disposition Kinetics of Tacrolimus: Studies in mdr la Knockout Mice
Purpose. This study was performed to evaluate the involvement of P-glycoprotein in disposition kinetics of tacrolimus (FK506), a substrate of P-glycoprotein, in the body.
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Article
Gas-liquid chromatographic analysis of geometrical and positional octadecenoic and octadecadienoic acid isomers produced by catalytic hydrogenation of linoleic acid on Ir/Al2O3
Catalytic hydrogenation of linoleic acid was studied on Ir/Al2O3. A detailed analysis of geometrical and positional isomers of octadecenoic acid (18:1) in the products was performed by capillary gas-liquid chroma...
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Article
Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM), the most common cause of sudden death in the young, is an autosomal dominant disease characterized by ventricular hypertrophy accompanied by myofibrillar disarrays1. Linkage stu...
