25 Result(s)
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Michihiro C. Yoshida
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Article
Differentiation of Z and W Chromosomes Revealed by Replication Banding and FISH Map** of Sex-chromosome-linked DNA Markers in the Cassowary (Aves, Ratitae)
We identified sex chromosomes of the double-wattled cassowary (Casuarius casuarius) by a replication banding method. The acrocentric Z chromosome, the fifth largest pair in males and slightly smaller W chromos...
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Kin-related social organization in a winter population of the voleClethrionomys rufocanus
Kinship amongClethrionomys rufocanus was investigated during the winter of 1992/93 in a 3-ha enclosure using both molecular and catch-mark-release techniques. Forty-six adult voles (22 males and 24 females) havin...
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Molecular Phylogenetic Inference of the Woolly Mammoth Mammuthus primigenius, Based on Complete Sequences of Mitochondrial Cytochrome b and 12S Ribosomal RNA Genes
Complete sequences of cytochrome b (1,137 bases) and 12S ribosomal RNA (961 bases) genes in mitochondrial DNA were successfully determined from the woolly mammoth (Mammuthus primigenius), African elephant (Loxod...
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Human class III POU genes, POU3F1 and POU3F3, map to Chromosomes 1p34.1 and 3p14.2
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Uniparental chromosome elimination in the early embryogenesis of the inviable salmonid hybrids between masu salmon female and rainbow trout male
Chromosome elimination through chromosome loss and partial deletion is known to be one of the causes of embryonic inviability in some salmonid interspecific hybrids. Using fluorescence in situ hybridization an...
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Article
Differences in the chromosomal distribution of telomeric (TTAGGG) n sequences in two species of the vespertilionid bats
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Chromosomal Analysis of Spontaneous Hepatomas, a Derived Cell Line, and Chemically Induced Hepatomas in LEC Rats
Recent banding studies of chromosomes in a variety of human and animal tumors have provided a growing body of evidence that certain specific or nonrandom chromosomal changes are causally related to or closely ...
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Hepatoma-Associated Alterations of Serum α1-Antitrypsin in LEC Rats
LEC rats have been established as a new mutant strain which develops hereditary hepatitis [1–3] and spontaneous hepatocellular carcinomas (hepatomas) [4]. However, the mechanisms of the development of the sequ...
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Chromosomal Map** of the Placental Glutathione S-Transferase Gene and Its Expression in Livers of LEC Rats
The LEC strain rat is a new mutant which suddenly suffers from fulminant hepatitis at about 4 months of age [1, 2]. A crossing test of LEC rats showed that the hepatitis has an autosomal recessive mode of inhe...
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Reproductive Performance and Effects of Pregnancy on the Acute Phase of Hepatitis in LEC Rats
LEC rats have been established as a mutant strain that suffers from fulminant hepatitis and severe jaundice at about 4 months of age [1, 2]. The clinical symptoms of hepatitis include severe jaundice, a bleedi...
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Chapter
Hereditary Low Levels of Plasma Ceruloplasmin in LEC Rats
The LEC rats with hereditary hepatitis show an abnormal accumulation of copper in various organs such as liver, kidney, and brain, together with a marked decrease in the level of serum or plasma ceruloplasmin ...
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High Susceptibility to Spontaneous Development of Hepatocellular Carcinoma in LEC Rats
Spontaneous hepatitis was first found in the LEC strain rat, which had been maintained conventionally at the Center for Experimental Plants and Animals, Hokkaido University [1]. The hepatitis appears suddenly ...
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Drug-Metabolizing Ability and Inducibility of Chromosomal Aberrations and Sister Chromatid Exchanges in LEC Rats Exposed to Cyclophosphamide
The LEC rat strain is a new mutant characterized by the spontaneous development of hepatitis with severe jaundice about 4 months of age [1, 2]. Genetic analysis demonstrated that the disease has an autosomal r...
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Origin of the LEC Strain with a New Mutation Causing Hereditary Hepatitis
Over the last 10 years, a large number of animal models for human diseases has been discovered in laboratory mice and rats. Such model animals have become an indispensable tool in many fields of biological and...
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Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain
XERODERMA pigmentosum (XP) is an autosomal recessive disease, characterized by a high incidence of sunlight-induced skin cancer. Cells from people with this condition are hypersensitive to ultraviolet because ...
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Nuclear Genes Encoding Two Subunits of Human Mitochondrial Cytochrome bc1 Complex, Cytochrome c1 and Ubiquinone-Binding Protein: Their Structural Organization of the 5′-Flanking Regions and Chromosomal Localization
We have isolated nuclear genes encoding human cytochrome c1 (C1) and ubiquinone-binding protein (QP) of cytochrome bc1 complex. The C1 and QP genes span 2.4 and 4.5 kilobase pairs, respectively. All intron/exon s...
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Molecular cloning and chromosomal assignment of a human perforin (PFP) gene
Human perforin cDNA was isolated and the complete nucleotide sequence of the gene determined. The deduced amino acid sequence of human perforin showed 68.4% similarity to that of mouse perforin. RNA blot analy...
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Human gene coding for granulocyte-colony stimulating factor is assigned to the q21-q22 region of chromosome 17
Granulocyte-colony stimulating factor (G-CSF) is a member of colony stimulating factors which regulate the proliferation and differentiation of hematopoietic progenitor cells. A full-length cDNA ...
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Regional assignment of five genes on human chromosome 19
A human-mouse hybrid segregant HM76Dd40-6 with new characteristics was derived from the hybrid cell line HM76Dd containing human chromosome 19 as the only human chromosome. Three virus sensitivities located on...
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Induction of supermelanin synthesis and morphological changes in interspecific reconstituted cells and its reversal by tumor promoter
Chloramphenicol-resistant (CAP r) reconstituted cells and cybrids were isolated by fusion of karyoplasts (or intact cells) of mouse amelanotic melanoma B16 cells with cytoplasts of hypoxanthine-guanine phosphori...
