-
Article
Open AccessModeling brain network flexibility in networks of coupled oscillators: a feasibility study
Modeling the functionality of the human brain is a major goal in neuroscience for which many powerful methodologies have been developed over the last decade. The impact of working memory and the associated br...
-
Article
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC
Immunotherapy revolutionized treatment options in cancer, yet the mechanisms underlying resistance in many patients remain poorly understood. Cellular proteasomes have been implicated in modulating antitumor i...
-
Article
Open AccessConcurrent neuroimaging and neurostimulation reveals a causal role for dlPFC in coding of task-relevant information
Dorsolateral prefrontal cortex (dlPFC) is proposed to drive brain-wide focus by biasing processing in favour of task-relevant information. A longstanding debate concerns whether this is achieved through enhanc...
-
Article
Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung
A Correction to this paper has been published: https://doi.org/10.1038/s41586-020-03087-6
-
Article
Inhibition of LTβR signalling activates WNT-induced regeneration in lung
Lymphotoxin β-receptor (LTβR) signalling promotes lymphoid neogenesis and the development of tertiary lymphoid structures1,2, which are associated with severe chronic inflammatory diseases that span several organ...
-
Article
Open AccessInter-slice leakage and intra-slice aliasing in simultaneous multi-slice echo-planar images
Simultaneous multi-slice (SMS) imaging is a popular technique for increasing acquisition speed in echo-planar imaging (EPI) fMRI. However, SMS data are prone to motion sensitivity and slice leakage artefacts, ...
-
Article
Open AccessAn EEG study of detection without localisation in change blindness
Previous studies of change blindness have suggested a distinction between detection and localisation of changes in a visual scene. Using a simple paradigm with an array of coloured squares, the present study a...
-
Chapter
Characterizing Flows by Complex Network Methods
During the last years, complex network approaches have demonstrated their great potentials as versatile tools for exploring the structural as well as dynamical properties of complex systems from a variety of d...
-
Article
Open AccessDifferential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Repetitive injury and reprogramming of the lung epithelium are thought to be critical drivers of disease progression, contributing to f...
-
Article
Open AccessFK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis
In idiopathic pulmonary fibrosis (IPF), fibroblasts gain a more migratory phenotype and excessively secrete extracellular matrix (ECM), ultimately leading to alveolar scarring and progressive dyspnea. Here, we...
-
Article
Open Access31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one
-
Article
Comprehensive genomic profiles of small cell lung cancer
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. In nearly all the tumours analysed we found bi-allelic inactivation of TP53 and RB1, sometimes by complex g...
-
Article
Open AccessBlood-sampling collection prior to surgery may have a significant influence upon biomarker concentrations measured
Biomarkers can be subtle tools to aid the diagnosis, prognosis and monitoring of therapy and disease progression. The validation of biomarkers is a cumbersome process involving many steps. Serum samples from l...
-
Chapter
Transfer Entropy in Neuroscience
Information transfer is a key component of information processing, next to information storage and modification. Information transfer can be measured by a variety of directed informationmeasures of which trans...
-
Article
Open AccessTRENTOOL: A Matlab open source toolbox to analyse information flow in time series data with transfer entropy
Transfer entropy (TE) is a measure for the detection of directed interactions. Transfer entropy is an information theoretic implementation of Wiener's principle of observational causality. It offers an approac...
-
Article
Open AccessTRENTOOL: an open source toolbox to estimate neural directed interactions with transfer entropy
-
Article
Open AccessTransfer entropy—a model-free measure of effective connectivity for the neurosciences
Understanding causal relationships, or effective connectivity, between parts of the brain is of utmost importance because a large part of the brain’s activity is thought to be internally generated and, hence, ...
-
Article
Atrial Resection for Lung Cancer: Morbidity, Mortality, and Long-Term Follow-up
The purpose of this study was to examine our results of combined resection of the atrium and non-small-cell lung cancer using a concurrent and continuously updated database.
-
Article
A representation for coordination fault detection in large-scale multi-agent systems
Teamwork requires that team members coordinate their actions. The representation of the coordination is a key requirement since it influences the complexity and flexibility of reasoning team-members. One aspec...
-
Article
Object- and direction-specific interference between manual and mental rotation
We conducted a series of psychophysical experiments to investigate the nature and specificity of behavioral interference between mental and manual rotation. Participants were asked to mentally rotate five diff...
