-
Article
Open AccessSignificance of PSCA as a novel prognostic marker and therapeutic target for cancer
One of the contributing factors in the diagnosis and treatment of most cancers is the identification of their surface antigens. Cancer tissues or cells have their specific antigens. Some antigens that are pres...
-
Article
Open AccessAnti-oral cancer properties of potential probiotic lactobacilli isolated from traditional milk, cheese, and yogurt
This study investigates the probiotic and anti-cancer effects of 21 isolated Lactobacillus strains from cheese, milk, and yogurt in Kermanshah, Iran, on oral cancer cell lines KB and OSCC. Four selected isolates ...
-
Article
A two-layer nanofiber-Tragacanth hydrogel composite containing Lavender extract and Mupirocin as a wound dressing
Dressing plays important role in wound healing. Hydrogels are three-dimensional structural systems with outstanding properties for wound dressing. However, conventional preformed hydrogels lack versatility in ...
-
Article
A sandwich electrospun nanofibers/Tragacanth hydrogel composite containing Aloe vera extract and silver sulfadiazine as a wound dressing
In the present study, a sandwich electrospun nanofibers/tragacanth hydrogel composite containing Aloe vera extract and silver sulfadiazine was prepared. The potential application was considered as a wound dressin...
-
Article
Synthesis, characterization, and antioxidant activity study of a novel Pt-cyclopropa[60]fullerene complex/graphene oxide nanozyme
Over the past few decades, multifunctional hybrid bio-nanomaterials have emerged as nanozyme antioxidants, which are a new interdisciplinary frontier between nanotechnology and life sciences. In this study, we...
-
Article
Green synthesis and biological activities assessment of some new chromeno[2,3-b]pyridine derivatives
Magnetite nanoparticles (MNPs) composed of γ-Fe2O3 and hydroxyapatite (HAp) were modified by hexamethylen-1,6-diisocyanate (HMDI) followed by thiourea dioxide and used as recyclable catalyst for the synthesis of ...
-
Article
A novel stimuli-responsive magnetic hydrogel based on nature-inspired tragacanth gum for chemo/hyperthermia treatment of cancerous cells
An efficient and facile strategy for the fabrication of a bioinspired drug delivery system (DDS) was designed and developed successfully based on tragacanth gum (TG) owing to its wide range of biological and p...
-
Article
Electroactive nanofibrous scaffold based on polythiophene for bone tissue engineering application
Electrically conductive polymeric biomaterials are promising candidates for bone tissue engineering (TE) due to pivotal role of electrical stimulation (ES) in regulating of some biological functions, including...
-
Article
Hyaluronic acid-based drug nanocarriers as a novel drug delivery system for cancer chemotherapy: A systematic review
Chemotherapy is the most common treatment strategy for cancer patients. Nevertheless, limited drug delivery to cancer cells, intolerable toxicity, and multiple drug resistance are constant challenges of chemot...
-
Article
A Novel pH-Responsive Magnetic Nanosystem for Delivery of Anticancer Drugs
A novel pH-responsive magnetic nanosystem was designed and developed for cancer therapy. For this purpose, a well-defined terpolymer was synthesized through the polymerization of 2-hydroxyethyl methacrylate (H...
-
Article
Open AccessTarkhineh as a new microencapsulation matrix improves the quality and sensory characteristics of probiotic Lactococcus lactis KUMS-T18 enriched potato chips
In the present study, probiotic potato chips containing a newly isolated probiotic Lactococcus lactis KUMS-T18 strain were produced by using a simple spraying method and then enhancing the stability, survival rat...
-
Article
Open AccessPseudohomogeneous metallic catalyst based on tungstate-decorated amphiphilic carbon quantum dots for selective oxidative scission of alkenes to aldehyde
Herein, we present an interesting role of tungstate-decorated amphiphilic carbon quantum dots (A-CQDs/W) in the selective oxidative cleavage of alkenes to aldehydes. In this work, for the first time, we disclo...
-
Article
Thermal-responsive magnetic hydrogels based on Tragacanth gum for delivery of anticancer drugs
Thermal-responsive magnetic hydrogels (Hydrogel 1 and Hydrogel 2) were synthesized through the copolymerization of maleic anhydride-functionalized Tragacanth gum macromonomer (MATGM), N-isopropylacrylamide (NIPAA...
-
Article
Multi-stimuli-responsive magnetic hydrogel based on Tragacanth gum as a de novo nanosystem for targeted chemo/hyperthermia treatment of cancer
A novel magnetic pH- and redox-responsive drug delivery system (DDS) based on natural Tragacanth gum (TG) was developed for targeted chemo/hyperthermia treatment of cancer. Firstly, acrylic acid (AA) monomer w...
-
Article
Electrically Conductive Nanofibers Composed of Chitosan-grafted Polythiophene and Poly(ε-caprolactone) as Tissue Engineering Scaffold
Two novel electrically conductive nanofibrous scaffolds based on chitosan-grafted polythiophene (CS-g-PTh), and chitosan-grafted polythiophene/poly(ε-caprolactone) (CS-g-PTh/PCL) have been fabricated through elec...
-
Article
Open AccessHuman plasma protein corona decreases the toxicity of pillar-layer metal organic framework
This scenario was designed to investigate the protein corona pattern on the pillar-layer surface of a Cu-based metal–organic framework (MOF) in human plasma. The [Cu(L)(L/)].1.3DMA (MOF-1) {L = 4, 4/-bipyridine a...
-
Article
A Thermal-Responsive Y-Shaped Miktoarm Amphiphilic Block Copolymer Composed of Poly(ε-caprolactone) and Poly(N-isopropylacrylamide) as a Nano-micellar Carrier for Anti-cancer Drugs
A thermal-responsive Y-shaped amphiphilic block copolymer, namely poly(N-isopropylacrylamide-block-[poly(ε-caprolactone)]2 (PNIPAAm-b-PCL2), was synthesized through the combination of atom transfer radical polyme...
-
Article
A dual stimuli-responsive star-shaped nanocarrier as de novo drug delivery system for chemotherapy of solid tumors
A novel pH- and temperature-responsive star-shaped terpolymer, namely star shaped-poly(ε-caprolactone)-grafted-[poly(N,N′-dimethylamino)ethyl methacrylate-block-poly(N-isopropylacrylamide)] [s-PCL-g-(PDMAEMA-b-PN...
-
Article
Conducting polymer-based electrically conductive adhesive materials: design, fabrication, properties, and applications
In the past few decades, increasing demands for electrically conductive adhesives (ECAs) have led to growing interest in the design and development of innovative strategies to obtain materials with synergetic ...
-
Article
Open AccessTumor microenvironment complexity and therapeutic implications at a glance
The dynamic interactions of cancer cells with their microenvironment consisting of stromal cells (cellular part) and extracellular matrix (ECM) components (non-cellular) is essential to stimulate the heterogen...
