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  1. Article

    Open Access

    Cross-protective antibodies against common endemic respiratory viruses

    Respiratory syncytial virus (RSV), human metapneumovirus (HMPV), and human parainfluenza virus types one (HPIV1) and three (HPIV3) can cause severe disease and death in immunocompromised patients, the elderly,...

    Madelyn Cabán, Justas V. Rodarte, Madeleine Bibby, Matthew D. Gray… in Nature Communications (2023)

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  2. Article

    Open Access

    Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice

    VRC01-class broadly neutralizing HIV-1 antibodies protect animals from experimental infection and could contribute to an effective vaccine response. Their predicted germline forms (gl) bind Env inefficiently, ...

    Andrew T. McGuire, Matthew D. Gray, Pia Dosenovic… in Nature Communications (2016)

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  3. No Access

    Article

    The premature ageing syndrome protein, WRN, is a 3′→5′ exonuclease

    Shurong Huang, Baomin Li, Matthew D. Gray, Junko Oshima, I. Saira Mian… in Nature Genetics (1998)

  4. No Access

    Article

    The human FE65 gene: genomic structure and an intronic biallelic polymorphism associated with sporadic dementia of the Alzheimer type

    The FE65 protein binds to the intracellular domain of the beta-amyloid precursor protein (ßPP) and may modulate the internalization of ßPP. This gene is highly expressed in regions of the brain specifically a...

    Q. Hu, Walter A. Kukull, Steven L. Bressler, Matthew D. Gray… in Human Genetics (1998)

  5. No Access

    Article

    The Werner syndrome protein is a DNA helicase

    Werner syndrome (WS) is an uncommon autosomal recessive disorder characterized by premature aging. The clinical manifestations of WS, including atherosclerosis and osteoporosis, appear early in adulthood, and ...

    Matthew D. Gray, Jiang-Cheng Shen, Ashwini S. Kamath-Loeb, A. Blank… in Nature Genetics (1997)