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Article
Open AccessOcular Manifestations in Juvenile Behçet’s Disease: A Registry-Based Analysis from the AIDA Network
This study aims to characterize ocular manifestations of juvenile Behçet’s disease (jBD).
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Article
Open AccessUnfolding dermatologic spectrum of Behçet’s disease in Italy: real-life data from the International AIDA Network Behçet’s disease Registry
Behçet’s disease (BD) is a heterogeneous multifactorial autoinflammatory disease characterized by a plethora of clinical manifestations. Cutaneous lesions are considered hallmarks of the disease. However, thei...
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Article
Open AccessMusculoskeletal manifestations in children with Behçet’s syndrome: data from the AIDA Network Behçet’s Syndrome Registry
This study aims to describe musculoskeletal manifestations (MSM) in children with Behçet’s syndrome (BS), their association with other disease manifestations, response to therapy, and long-term prognosis. Data...
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Article
Open AccessAccrual of organ damage in Behçet’s syndrome: trajectory, associated factors, and impact on patients’ quality of life over a 2-year prospective follow-up study
This study aimed to investigate the trajectory of damage accrual, associated factors, and impact on health-related quality of life (HR-QoL) in a multicenter cohort of patients with Behçet’s syndrome (BS) over ...
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Article
Open AccessDevelopment and implementation of the AIDA International Registry for patients with Behçet’s disease
Purpose of the present paper is to point out the design, development and deployment of the AutoInflammatory Disease Alliance (AIDA) International Registry dedicated to pediatric and adult patients with Behçet’...
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Article
Open AccessAn Italian Multicenter Study on Anti-NXP2 Antibodies: Clinical and Serological Associations
The identification of anti-NXP2 antibodies is considered a serological marker of dermatomyositis (DM), with calcinosis, severe myositis and, in some reports, with cancer. Historically, these associations with ...
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Article
Open AccessLong-term glucocorticoid treatment and high relapse rate remain unresolved issues in the real-life management of polymyalgia rheumatica: a systematic literature review and meta-analysis
A systematic review and meta-analysis were conducted, according to the PRISMA methodology, to summarize current evidence on the prevalence and predictors of long-term glucocorticoid (GC) treatment and disease ...
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Article
Open AccessBiologics and Targeted Synthetic Drugs Can Induce Immune-Mediated Glomerular Disorders in Patients with Rheumatic Diseases: An Updated Systematic Literature Review
Our objective was to update the understanding of the development of paradoxical immune-mediated glomerular disorders (IGDs) in patients with rheumatic diseases treated with biologics and targeted synthetic dru...
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Article
Open AccessDiscordance between patient and physician global assessment of disease activity in Behçet’s syndrome: a multicenter study cohort
To compare the patients’ and physician’s global assessment of disease activity in Behçet’s syndrome (BS) and investigate the frequency, magnitude, and determinants of potential discordance.
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Article
Effect of carotid image-based phenotypes on cardiovascular risk calculator: AECRS1.0
Today, the 10-year cardiovascular risk largely relies on conventional cardiovascular risk factors (CCVRFs) and suffers from the effect of atherosclerotic wall changes. In this study, we present a novel risk ca...
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Article
Rheumatoid Arthritis: Atherosclerosis Imaging and Cardiovascular Risk Assessment Using Machine and Deep Learning–Based Tissue Characterization
Rheumatoid arthritis (RA) is a chronic, autoimmune disease which may result in a higher risk of cardiovascular (CV) events and stroke. Tissue characterization and risk stratification of patients with rheumatoi...
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Article
Open AccessAn allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes
The Endoplasmatic Reticulum Aminopeptidases ERAP1 and ERAP2 are implicated in a variety of immune and non-immune functions. Most studies however have focused on their role in sha** the HLA class I peptidome by ...
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Article
Open AccessFailure to achieve lupus low disease activity state (LLDAS) six months after diagnosis is associated with early damage accrual in Caucasian patients with systemic lupus erythematosus
The aim was to assess the attainability and outcome of the lupus low disease activity state (LLDAS) in the early stages of systemic lupus erythematosus (SLE).
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Article
Open AccessUltrasonographic assessment of bone erosions in the different subtypes of systemic lupus erythematosus arthritis: comparison with computed tomography
The aim was to determine the accuracy of high-resolution ultrasonography (US) for detecting erosion in the metacarpophalangeal (MCP) and wrist joints of patients with different subtypes of systemic lupus eryth...
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Article
Population-based analysis of hospitalizations for patients with systemic sclerosis in a West-European region over the period 2001–2012
The aim of this study was to evaluate systemic sclerosis (SSc) hospitalizations through a retrospective population-based study analyzing administrative data during 2001–2012 in Sardinia, an Italian region wit...
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Article
Open AccessThe Ankylosing Spondylitis-Associated HLA-B*2705 Presents a B*0702-Restricted EBV Epitope and Sustains the Clonal Amplification of Cytotoxic T Cells in Patients
HLA-B*27 is strongly associated with an inflammatory autoimmune disorder, the Ankylosing Spondylitis (AS) and plays a protective role in viral infections. The two aspects might be linked. In this work, we compare...
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Article
Open AccessPrognostic impact of coronary microcirculation abnormalities in systemic sclerosis: a prospective study to evaluate the role of non-invasive tests
Microcirculation dysfunction is a typical feature of systemic sclerosis (SSc) and represents the earliest abnormality of primary myocardial involvement. We assessed coronary microcirculation status by combinin...
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Chapter and Conference Paper
An Integrated Portable Device for the Hand Functional Assessment in the Clinical Practice
The functionality of the human hand is of paramount importance for the daily life activity of a subject. Several chronic diseases can have localized lesions on the hands, causing disability, as for the Systemi...
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Article
New hybrid inorganic-organic proton conducting membranes based on Nafion and a [(ZrO2)⋅(Ta2O5)0.119] oxide core-shell nanofiller
Hybrid inorganic-organic proton-conducting membranes are prepared by a standard solvent casting procedure. Nafion® is used as the host polymer and [(ZrO2)⋅(Ta2O5)0.119] “core-shell” nanoparticles (d ~ 10-50 nm) a...
