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Article
Activation of NFκB Represents the Central Event in the Neoplastic Progression Associated with Barrett's Esophagus: A Possible Link to the Inflammation and Overexpression of COX-2, PPARγ and Growth Factors
The molecular mechanisms responsible for the progression of malignant transformation in Barrett's esophagus (BE) are still poorly understood. This study was undertaken (1) to investigate the gene and protein e...
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Article
Neue Deklarationspflicht für Nahrungsmittelallergene in Lebensmitteln
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Article
Standardisierung von oralen Provokationstests bei Nahrungsmittelallergien
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Article
Decreased Histamine Catabolism in the Colonic Mucosa of Patients with Colonic Adenoma
Alterations in mucosal histamine degradation play an important role in various gastrotinestinal diseases including colonic adenoma. In humans, histamine can be catabolized either by oxidative deamination by di...
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Article
Hauttestungen mit Nahrungsmittelallergenen
Hauttestungen haben einen zentralen Stellenwert in der Abklärung von Sensibilisierungen bei Nahrungsmittelallergien. Insbesondere der Pricktest stellt eine Routinemethode dar. Allerdings komplizieren instabile...
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Article
Vorgehen bei vermuteter Nahrungsmittelallergie bei atopischer Dermatitis
In der vorliegenden Leitlinie der Arbeitsgruppe Nahrungsmittelallergie der DGAKI und des ÄDA werden verschiedene Vorgehensweisen bei vermuteter Nahrungsmittelallergie bei atopischer Dermatitis (Neurodermitis, ...
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Article
Mastozytose
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Article
Keine Empfehlung für IgG- und IgG4-Bestimmungen gegen Nahrungsmittel
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Article
Fruktosemalabsorption
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Article
Therapiemöglichkeiten bei der IgE-vermittelten Nahrungsmittelallergie
Erst nachdem die klinische Relevanz einer Nahrungsmittelallergie eindeutig nachgewiesen ist, erfolgt die therapeutische Intervention. Hierbei stellt die Karenz den wichtigsten Pfeiler dar. Wegen der Komplexitä...
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Article
Die systemische Mastozytose – Standortbestimmung einer internistischen Erkrankung
Die systemische Mastozytose ist eine Erkrankung, bei der sich genetisch krankhaft veränderte Mastzellen aufgrund einer erhöhten Proliferationsrate und verminderten Apoptose in allen Organen und Geweben anreich...
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Article
Open AccessChronic calcium pyrophosphate crystal inflammatory arthritis induced by extreme hypomagnesemia in short bowel syndrome
Short bowel syndrome (SBS) may induce a plethora of clinical symptoms ranging from underweight to nutrient-, vitamin- and electrolyte deficiencies. The objective of this case report is to illustrate how demand...
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Article
Over-the-Scope Clip Application Yields a High Rate of Closure in Gastrointestinal Perforations and May Reduce Emergency Surgery
Perforation of the gastrointestinal tract may cause various complications and may require emergency surgery, even in patients with significant comorbidities.
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Article
Activation of the transcription factor Nrf2 in macrophages, Caco-2 cells and intact human gut tissue by Maillard reaction products and coffee
In addition to direct antioxidative effects, Maillard reaction products (MRPs) could increase the antioxidative capacity of cells through the induction of cytoprotective enzymes. Since many of those enzymes ar...
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Article
Intravenous infusion of ascorbic acid decreases serum histamine concentrations in patients with allergic and non-allergic diseases
Histamine plays an important role in the development of symptoms in allergic, infectious, neoplastic and other diseases. Empirical findings have suggested beneficial effects of ascorbic acid supplementation in...
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Article
Open AccessOsteonecrosis of the jaw in a Crohn’s disease patient following a course of Bisphosphonate and Adalimumab therapy: a case report
Bisphosphonates have a widespread indication for osteoporosis and are also applied in cancer patients with skeletal-related conditions. Bisphosphonate-associated osteonecrosis of the jaw (BRONJ) is a feared si...
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Article
Nahrungsmittelallergie infolge immunologischer Kreuzreaktivitäten mit Inhalationsallergenen
Bei älteren Kindern, Jugendlichen und Erwachsenen wird ein großer Teil Immunglobulin-E(IgE)-vermittelter Nahrungsmittelallergien durch kreuzreaktive allergene Strukturen ausgelöst. Die primäre Sensibilisierung...
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Article
Food allergies resulting from immunological cross-reactivity with inhalant allergens
A large proportion of immunoglobulin E (IgE)-mediated food allergies in older children, adolescents and adults are caused by cross-reactive allergenic structures. Primary sensitization is most commonly to inha...
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Article
Open AccessEosinophilic gastroenteritis with refractory ulcer disease and gastrointestinal bleeding as a rare manifestation of seronegative gastrointestinal food allergy
Gastrointestinal bleeding and iron deficiency anaemia may cause severe symptoms and may require extensive diagnostics and substantial amounts of health resources.
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Article
Outcome and complications of endoscopic balloon dilatations in various types of ileocaecal and colonic stenosis in patients with Crohn’s disease
We examined the outcome and the complications of endoscopic balloon dilatation (EBD) of ileocaecal and colonic strictures due to Crohn’s disease.
