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  1. Article

    Open Access

    The role of community pharmacists in optimising patient self-management of constipation: an inter-disciplinary consensus view

    Constipation is a common gastrointestinal disorder that may occur as occasional (acute) episodes, but can also persist over longer periods of time. Patients usually self-diagnose and self-manage constipation w...

    Thomas Frieling, Eric Martin, Steffen Fischer, Daniel Pohl… in Drugs & Therapy Perspectives (2023)

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  2. No Access

    Chapter

    Pathophysiologie der gastroösophagealen Refluxkrankheit

    Die der gastroösophagealen Refluxkrankheit ist komplex und umfasst anatomische Veränderungen und neurogene bzw. myogene Funktionsstörungen der gastroösophagealen Barriere, Verminderung der , , Veränderunge...

    Thomas Frieling in Gastroösophageale Refluxerkrankung (2023)

  3. Article

    Open Access

    The serotonin receptor 3E variant is a risk factor for female IBS-D

    Irritable bowel syndrome (IBS) is a gut-brain disorder of multifactorial origin. Evidence of disturbed serotonergic function in IBS accumulated for the 5-HT3 receptor family. 5-HT3Rs are encoded by HTR3 genes and...

    Nikola Fritz, Sabrina Berens, Yuanjun Dong… in Journal of Molecular Medicine (2022)

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    Article

    Comparative analysis of mutation of tyrosine kinase kit in mast cells from patients with systemic mast cell activation syndrome and healthy subjects

    Systemic mast cell activation syndrome is a mast cell disorder characterized by an unregulated increased activation of mast cells leading to a pathologically enhanced release of mediators. Mutations in tyrosin...

    Gerhard J. Molderings, Kirsten Meis, Ulrich W. Kolck, Jürgen Homann… in Immunogenetics (2010)

  5. No Access

    Article

    Die systemische Mastozytose – Standortbestimmung einer internistischen Erkrankung

    Die systemische Mastozytose ist eine Erkrankung, bei der sich genetisch krankhaft veränderte Mastzellen aufgrund einer erhöhten Proliferationsrate und verminderten Apoptose in allen Organen und Geweben anreich...

    Jürgen Homann, Ulrich W. Kolck, Andreas Ehnes, Thomas Frieling… in Medizinische Klinik (2010)

  6. No Access

    Reference Work Entry In depth

    Nausea and Vomiting

    Thomas Frieling in Encyclopedia of Molecular Mechanisms of Disease (2009)

  7. No Access

    Reference Work Entry In depth

    Intestinal Obstruction, Functional

    Thomas Frieling in Encyclopedia of Molecular Mechanisms of Disease (2009)

  8. No Access

    Reference Work Entry In depth

    Achalasia

    Thomas Frieling in Encyclopedia of Molecular Mechanisms of Disease (2009)

  9. No Access

    Reference Work Entry In depth

    Esophageal Spasm

    Thomas Frieling in Encyclopedia of Molecular Mechanisms of Disease (2009)

  10. No Access

    Reference Work Entry In depth

    Odynophagia

    Thomas Frieling in Encyclopedia of Molecular Mechanisms of Disease (2009)

  11. No Access

    Reference Work Entry In depth

    Constipation, Functional

    Thomas Frieling in Encyclopedia of Molecular Mechanisms of Disease (2009)

  12. No Access

    Chapter

    Ösophaguserkrankungen

    Thomas Frieling, Stephan Petrasch, Thomas Rösch in Medizinische Therapie 2005|2006 (2005)

  13. No Access

    Chapter

    Erkrankungen des Magen-Darm-Traktes

    Eine gastroösophageale Refluxkrankheit (GERD) liegt vor, wenn ein Risiko für organische Komplikationen durch einen gesteigerten gastroösophagealen Reflux (GER) und/oder eine signifikante Störung der Lebensqual...

    Thomas Frieling, Stephan Petrasch, T. Röscx… in Medizinische Therapie in Klinik und Praxis (2003)

  14. Article

    Open Access

    Expense and benefit of neoadjuvant treatment in squamous cell carcinoma of the esophagus

    The effectiveness of neoadjuvant treatment (NT) prior to resection of squamous cell carcinoma of the esophagus (SCCE) in terms of prolonged survival has not been proven by randomized trials. Facing considerabl...

    Joachim W Heise, Hansjörg Heep, Thomas Frieling, Mario Sarbia… in BMC Cancer (2001)

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  15. No Access

    Article

    Extraesophageal Autonomic Dysfunction in Patients with Achalasia

    A disagreement exists as to whetherextraintestinal parasympathetic autonomic function isaltered in patients with esophageal achalasia.Therefore, we assessed autonomic dysfunction inesophageal achalasia and con...

    Walter Olk, Boris Kiesewalter, Peter Auer, Paul Enck… in Digestive Diseases and Sciences (1999)

  16. No Access

    Article

    Treatment of radiation proctitis with hyperbaric oxygen: What is the optimal number of HBO treatments?

    Our objective was to investigate the effectiveness of hyperbaric oxygenation (HBO) in the treatment of radiation proctitis. The current literature was reviewed with regard to the necessary number of HBO treatm...

    Ulrich M. Carl, Doreen Peusch-Dreyer, Thomas Frieling… in Strahlentherapie und Onkologie (1998)