3 Result(s)

Article

CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage

The BH3-only protein NOXA is a regulator of mitochondrial apoptosis by specifically antagonizing the anti-apoptotic protein MCL-1. Here we show that the E3 ubiquitin ligase CHIP controls NOXA stability after D...

Marie-Christine Albert, Kerstin Brinkmann, Wojciech Pokrzywa… in Cell Death & Disease (2020)

Article

NOX enzymes as drug targets

Karl-Heinz Krause, David Lambeth, Martin Krönke in Cellular and Molecular Life Sciences (2012)

Article

Gene transfer of Hodgkin cell lines via multivalent anti-CD30 scFv displaying bacteriophage

The display of binding ligands, such as recombinant antibody fragments, on the surface of filamentous phage makes it possible to specifically attach these phage particles to target cells. After uptake of the p...

Yoon-Suk A Chung, Katja Sabel, Martin Krönke, Alexander Klimka in BMC Molecular Biology (2008)