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Article
Open AccessEpidemiology and risk factors of community-acquired pneumonia in patients with different causes of immunosuppression
Immunosuppression constitutes a significant risk for community-acquired pneumonia (CAP). Nevertheless, specific causes of immunosuppression and their relevance for incidence, etiology and prognosis of CAP are ...
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Article
Open AccessValidation of risk scores for prediction of severe pneumonia in kidney transplant recipients hospitalized with community-acquired pneumonia
Risk scores for community-acquired pneumonia (CAP) are widely used for standardized assessment in immunocompetent patients and to identify patients at risk for severe pneumonia and death. In immunocompromised ...
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Article
Open AccessUnmet needs in pneumonia research: a comprehensive approach by the CAPNETZ study group
Despite improvements in medical science and public health, mortality of community-acquired pneumonia (CAP) has barely changed throughout the last 15 years. The current SARS-CoV-2 pandemic has once again highli...
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Article
Open AccessEarly post-discharge mortality in CAP: frequency, risk factors and a prediction tool
There are few data on mortality after discharge with community-acquired pneumonia (CAP). Therefore, we evaluated risk factors for 30-day post-discharge mortality after CAP. We included all patients of the pros...
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Article
Prognostic value of blood pressure drops during the first 24 h after hospital admission for risk stratification of community-acquired pneumonia: a retrospective cohort study
Current risk stratification in community-acquired pneumonia (CAP) does not incorporate the dynamic nature of CAP evolution. Study aim was to evaluate the predictive value of early blood pressure (BP) drop and ...
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Article
Comparison of the qSOFA and CRB-65 for risk prediction in patients with community-acquired pneumonia
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Article
MR-proADM Predicts Exercise Capacity and Survival Superior to Other Biomarkers in PH
Besides the established biomarker NT-proBNP, the new cardiovascular biomarkers MR-proANP, MR-proADM, Copeptin, and CT-proET-1 are promising to evaluate hemodynamics, exercise parameters, and prognosis in pati...
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Article
Exercise Capacity Affects Quality of Life in Patients with Pulmonary Hypertension
The objective of this prospective study was to evaluate the impact of exercise capacity, mental disorders, and hemodynamics on quality-of-life (QoL) parameters in patients with pulmonary arterial hypertension ...
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Article
Open AccessSerum cortisol predicts death and critical disease independently of CRB-65 score in community-acquired pneumonia: a prospective observational cohort study
Several biomarkers and prognostic scores have been evaluated to predict prognosis in community-acquired pneumonia (CAP). Optimal risk stratification remains to be evaluated. The aim of this study was to evalua...
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Article
Successful switch from long-term intravenous iloprost to non-invasive combination therapy in idiopathic pulmonary arterial hypertension
In Europe intravenous (IV) iloprost, an alternative to epoprostenol, is an accepted treatment option for severely compromised patients with idiopathic pulmonary arterial hypertension (IPAH). Once initiated, th...
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Article
Combination therapy for portopulmonary hypertension with intravenous iloprost and oral bosentan
Severe portopulmonary hypertension (PPHTN) is a rare complication of liver cirrhosis and carries a poor prognosis. In the last years, intravenous (IV) epoprostenol has been suggested to be the optimal medical ...
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Article
Short-Course Antimicrobial Therapy for Community-Acquired Pneumonia
Management of community-acquired pneumonia (CAP) remains surprisingly controversial. Optimal duration of antimicrobial therapy reflects one of the open questions due to the lack of sufficient randomized clinic...
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Article
High mortality from urothelial carcinoma despite regular tumor screening in patients with analgesic nephropathy after renal transplantation
Patients with end-stage renal failure due to analgesic nephropathy have an increased risk of develo** a urothelial carcinoma. To determine the impact of renal transplantation on the frequency of urothelial c...
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Malignancies in transplant patients under cyclosporine treatment for more than 10 years
Long-term immunosuppressive therapy after renal transplantation with different kinds of drugs carries an increased risk of development of malignant disease [1–4]. Except for preexisting or undetected cases mos...
