91 Result(s)

Article

Time course of metabolic findings in coronary occlusion and reperfusion and their role for assessing myocardial salvage

The techniques currently used to assess myocardial infarction are limited in their ability to determine the amount of viable myocardium after a temporary ischemic event. Blood flow and segmental function may n...

Markus Schwaiger in European Journal of Nuclear Medicine (1986)

Article

Imaging of metabolism and autonomic innervation of the heart by positron emission tomography

Positron emission tomography (PET) allows, in combination with multiple radiopharmaceuticals, unique physiological and biochemical tissue characterization. Tracers of blood flow, metabolism and neuronal functi...

Pierre Mélon, Markus Schwaiger in European Journal of Nuclear Medicine (1992)

Article

Whole-body positron emission tomography in clinical oncology: Comparison between attenuation-corrected and uncorrected images

The clinical need for attenuation correction of whole-body positron emission tomography (PET) images is controversial, especially because of the required increase in imaging time. In this study, regional trace...

Frank M. Bengel, Sibylle I. Ziegler, Norbert Avril… in European Journal of Nuclear Medicine (1997)

Article

Regional myocardial wall thickening and global ejection fraction in patients with low angiographic left ventricular ejection fraction assessed by visual and quantitative resting ECG-gated ^99mTc-tetrofosmin single-photon emission tomography and magnetic resonance imaging

We investigated the use of visual and quantitative technetium 99m tetrofosmin ECG-gated single-photon emission tomography (SPET) for the assessment of regional myocardial wall thickening (WT) and left ventric...

Jens C. Stollfuss, Felix Haas, Ichiro Matsunari… in European Journal of Nuclear Medicine (1998)

Article

Reproducibility of polar map generation and assessment of defect severity and extent assessment in myocardial perfusion imaging using positron emission tomography

The purpose of this study was to determine the reliability of new software developed for the analysis of cardiac tomographic data. The algorithm delineates the long axis and defines the basal plane and subseq...

Stephan G. Nekolla, Christa Miethaner, Ngoc Nguyen… in European Journal of Nuclear Medicine (1998)

Article

Metaiodobenzylguanidine scintigraphy of the heart: what have we learnt clinically?

Naoya Hattori, Markus Schwaiger in European Journal of Nuclear Medicine (2000)

Article

Non-invasive estimation of myocardial efficiency using positron emission tomography and carbon-11 acetate – comparison between the normal and failing human heart

The clearance kinetics of carbon-11 acetate, assessed by positron emission tomography (PET),can be combined with measurements of ventricular function for non-invasive estimation of myocardial oxygen consumptio...

Frank M. Bengel, Bernhard Permanetter… in European Journal of Nuclear Medicine (2000)

Article

In vivo imaging of herpes simplex virus type 1 thymidine kinase gene expression: early kinetics of radiolabelled FIAU

Previous studies have shown that the herpes simplex virus type 1 thymidine kinase gene (HSV1-tk), in combination with appropriate radiolabelled substrates (e.g. [I*]-2’-fluoro-2’-deoxy-5-iodo-1-β-d-arabinofuranos...

Roland Haubner, Norbert Avril… in European Journal of Nuclear Medicine (2000)

Article

O-(2-[¹⁸F]Fluoroethyl)-l-tyrosine and l-[methyl-¹¹C]methionine uptake in brain tumours: initial results of a comparative study

O-(2-[¹⁸F]Fluoroethyl)-l-tyrosine (FET) is a recently described amino acid analogue that has shown high accumulation in animal tumours. The aim of this study was to compare the uptake of FET with that of l-[meth...

Wolfgang A. Weber, Hans-Jürgen Wester… in European Journal of Nuclear Medicine (2000)

Article

Non-invasive assessment of the effect of cardiac sympathetic innervation on metabolism of the human heart

The role of cardiac sympathetic nerves in the regulation of myocardial metabolism is not well defined. Owing to the presence of incomplete reinnervation, heart transplant recipients provide a unique model to ...

Frank M. Bengel, Peter Ueberfuhr… in European Journal of Nuclear Medicine (2000)

Article

Global and regional functional measurements with gated FDG PET in comparison with left ventriculography

The purpose of this study was to validate the measurement of global and regional left ventricular cardiac function with ECG-gated fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) by comp...

Naoya Hattori, Frank M. Bengel, Julinda Mehilli… in European Journal of Nuclear Medicine (2001)

Article

A prototype high-resolution animal positron tomograph with avalanche photodiode arrays and LSO crystals

To fully utilize positron emission tomography (PET) as a non-invasive tool for tissue characterization, dedicated instrumentation is being developed which is specially suited for imaging mice and rats. Semicon...

Sibylle I. Ziegler, Bernd J. Pichler, Guido Boening… in European Journal of Nuclear Medicine (2001)

Article

Comparison of radioiodinated TOC, TOCA and Mtr-TOCA: the effect of carbohydration on the pharmacokinetics

Although somatostatin-based peptide receptor imaging (sst-PRI) and peptide receptor radiotherapy (sst-PRRT) of human endocrine tumours and their metastases has become a valuable method, the experience with ra...

Hans-Jürgen Wester, Margret Schottelius… in European Journal of Nuclear Medicine and M… (2002)

Article

Alterations of the sympathetic nervous system and metabolic performance of the cardiomyopathic heart

Little is known about the effects of altered sympathetic innervation on the efficiency of the cardiomyopathic heart. Thus, it was the aim of this study to determine non-invasively the relationship between the...

Frank M. Bengel, Bernhard Permanetter… in European Journal of Nuclear Medicine and M… (2002)

Article

PET imaging with [¹¹C]methyl-L-methionine for therapy monitoring in patients with rectal cancer

In this study we evaluated whether positron emission tomography (PET) using the amino acid [¹¹C]methyl-L-methionine (MET) may be used for therapy monitoring in patients with rectal cancer who are undergoing preo...

Hinrich Wieder, Katja Ott, Frank Zimmermann… in European Journal of Nuclear Medicine and M… (2002)

Article

Deferoxamine improves coronary vascular responses to sympathetic stimulation in patients with type 1 diabetes mellitus

Effects of oxygen-derived free radicals are suggested to be a potential pathogenic factor for endothelial dysfunction. In this study we sought to evaluate the effect of hydroxyl radicals on the human coronary...

Naoya Hattori, Oliver Schnell… in European Journal of Nuclear Medicine and M… (2002)

Article

O-(2-[¹⁸F]Fluoroethyl)-L-tyrosine (FET): a tracer for differentiation of tumour from inflammation in murine lymph nodes

High uptake of [¹⁸F]fluoro-2-deoxy-D-glucose (FDG) by inflammatory cells is a frequent cause of false positive results in lymph node (LN) staging by positron emission tomography. Previous studies suggest that ra...

Friederike C. Rau, Wolfgang A. Weber… in European Journal of Nuclear Medicine and M… (2002)

Article

Biodistribution and kinetics of ¹³¹I-labelled anti-CD20 MAB IDEC-C2B8 (rituximab) in relapsed non-Hodgkin's lymphoma

The native chimeric human-mouse anti-CD20 antibody IDEC-C2B8 (rituximab) is therapeutically applied in relapsed non-Hodgkin's lymphoma (NHL). The purpose of this study was to evaluate the distribution and pha...

Klemens Scheidhauer, Ingo Wolf… in European Journal of Nuclear Medicine and M… (2002)

Article

Dysregulation of coronary microvascular reactivity in asymptomatic patients with type 2 diabetes mellitus

In diabetic patients, a number of studies have suggested an impairment of vascular reactivity in response to vasodilatory stimuli. The pattern of dysregulation at the coronary microcirculatory level, however,...

Mitsuru Momose, Claudia Abletshauser… in European Journal of Nuclear Medicine and M… (2002)

Article

Highlights of the 15th Annual Congress of the European Association of Nuclear Medicine, Vienna, 2002

Markus Schwaiger in European Journal of Nuclear Medicine and Molecular Imaging (2003)