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Article
Open AccessCeRebrUm and CardIac Protection with ALlopurinol in Neonates with Critical Congenital Heart Disease Requiring Cardiac Surgery with Cardiopulmonary Bypass (CRUCIAL): study protocol of a phase III, randomized, quadruple-blinded, placebo-controlled, Dutch multicenter trial
Neonates with critical congenital heart disease (CCHD) undergoing cardiac surgery with cardiopulmonary bypass (CPB) are at risk of brain injury that may result in adverse neurodevelopment. To date, no therapy ...
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Article
Open AccessPredictors of Left Ventricular Outflow Tract Obstruction After Primary Interrupted Aortic Arch Repair
Left ventricular outflow tract obstruction is an important complication after interrupted aortic arch repair and subsequent interventions may adversely affect survival. Identification of patients at risk for o...
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Article
Open AccessExercise Capacity in Asymptomatic Adult Patients Treated for Coarctation of the Aorta
A reduced exercise capacity is a common finding in adult congenital heart disease and is associated with cardiovascular morbidity and mortality. However, data on exercise capacity in patients after repair of c...
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Article
Perioperative and bedside cerebral monitoring identifies cerebral injury after surgical correction of congenital aortic arch obstruction
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Article
Open AccessCerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery
A robust inflammatory response occurs in the hours and days following cerebral ischemia. However, little is known about the immediate innate immune response in the first minutes after an ischemic insult in hum...
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Article
Open AccessBedside prediction rule for infections after pediatric cardiac surgery
Infections after pediatric cardiac surgery are a common complication, occurring in up to 30% of cases. The purpose of this study was to develop a bedside prediction rule to estimate the risk of a postoperative...
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Article
Open AccessImpact of preoperative positron emission tomography in patients with severely impaired LV-function undergoing surgical revascularization
In patients with ischemic cardiomyopathy, coronary artery bypass grafting (CABG) offers an important therapeutic option but is still associated with high perioperative mortality. Although previous studies sugg...
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Article
Myocardial gene expression of matched hibernating and control tissue from patients with ischemic left ventricular dysfunction
Limited data are available in humans regarding the molecular biology of hibernating myocardium (HM). The aim of this study was to identify gene expression patterns distinctive for human HM. We compared in pati...
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Article
Aortoesophageal fistula due to double aortic arch and prolonged nasogastric intubation: case report and review of the literature
The authors present a patient and describe other cases from the literature which demonstrate that prolonged use of nasogastric tubes can result in life-threatening aortoesophageal fistula formation in patients...
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Article
Coral as a substitute for bone grafts in delayed sternal closure in neonates
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Article
Effect on coronary artery flow reserve and resistance in the remote area after acute coronary artery occlusion in the pig model
It has been reported that vasodilator function in remote myocardial regions supplied by “angiographically normal” coronary arteries is impaired in patients after acute myocardial infarction (MI). The aim of th...
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Article
Regional myocardial wall thickening and global ejection fraction in patients with low angiographic left ventricular ejection fraction assessed by visual and quantitative resting ECG-gated 99mTc-tetrofosmin single-photon emission tomography and magnetic resonance imaging
We investigated the use of visual and quantitative technetium 99m tetrofosmin ECG-gated single-photon emission tomography (SPET) for the assessment of regional myocardial wall thickening (WT) and left ventric...
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Introduction
I’ve been given the pleasant task of introducing tonight’s speaker. One of the clichés that is often used by people who have been asked to introduce a speaker, especially if the person is lazy, is the statemen...
