5 Result(s)
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Marion Wobser
Internal Medicine
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Living Reference Work Entry In depth
Kutane Lymphome
Hautlymphome umfassen ein breites Spektrum an prognostisch unterschiedlichen Subtypen, wobei T-Zell-Lymphome die häufigste Untergruppe darstellen. Für die endgültige Diagnosestellung ist eine sorgfältige klini...
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Article
Correction: The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression
A Correction to this paper has been published: https://doi.org/10.1038/s41388-020-01535-1
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Article
Open AccessThe transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression
The transcription factor NRF2 is the major mediator of oxidative stress responses and is closely connected to therapy resistance in tumors harboring activating mutations in the NRF2 pathway. In melanoma, such ...
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Article
Open AccessBRAF inhibition causes resilience of melanoma cell lines by inducing the secretion of FGF1
Approximately half of all melanoma patients harbour activating mutations in the serine/threonine kinase BRAF. This is the basis for one of the main treatment strategies for this tumor type, the targeted therap...
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Article
Open AccessCutaneous CD8+ Cytotoxic T-Cell Lymphoma Infiltrates: Clinicopathological Correlation and Outcome of 35 Cases
Cytotoxic CD8+ T-cell lymphomas are only rarely encountered and thus remain only poorly characterized. Our aim was to collect and correlate clinical and histological data of CD8+ skin lymphoma infiltrates to o...
