-
Article
Open AccessLoss of autophagy affects melanoma development in a manner dependent on PTEN status
-
Article
Correction: The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression
A Correction to this paper has been published: https://doi.org/10.1038/s41388-020-01535-1
-
Article
Open AccessThe transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression
The transcription factor NRF2 is the major mediator of oxidative stress responses and is closely connected to therapy resistance in tumors harboring activating mutations in the NRF2 pathway. In melanoma, such ...
-
Article
Open AccessCutaneous CD8+ Cytotoxic T-Cell Lymphoma Infiltrates: Clinicopathological Correlation and Outcome of 35 Cases
Cytotoxic CD8+ T-cell lymphomas are only rarely encountered and thus remain only poorly characterized. Our aim was to collect and correlate clinical and histological data of CD8+ skin lymphoma infiltrates to o...
-
Article
Open AccessRetinoic acid pathway activity in wilms tumors and characterization of biological responses in vitro
Wilms tumor (WT) is one of the most common malignancies in childhood. With current therapy protocols up to 90% of patients can be cured, but there is still a need to improve therapy for patients with aggressiv...
-
Chapter
Rechtliche Grundlagen für Leistungen der gesetzlichen Rentenversicherung
Das historisch gewachsene gegliederte System der Rehabilitation in der Bundesrepublik Deutschland basiert darauf, dass nicht ein einheitlicher Träger für die Erbringung dieser Sozialleistungen zuständig ist, s...
-
Article
Open AccessAnalysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas
Angioimmunoblastic T-cell lymphoma (AILT) represents a subset of T-cell lymphomas but resembles an autoimmune disease in many of its clinical aspects. Despite the phenotype of effector T-cells and high express...
-
Article
Nodal peripheral T-cell lymphomas and, in particular, their lymphoepithelioid (Lennert’s) variant are often derived from CD8+ cytotoxic T-cells
Nodal peripheral T-cell lymphomas are not well understood, and most of them are classified in the “not otherwise specified group” (PTCL-NOS). Data on their normal cellular derivation are ambiguous. Most periph...
-
Chapter
Gesetzliche Grundlagen der Rentenversicherung
Das historisch gewachsene gegliederte System der Rehabilitation in der Bundesrepublik Deutschland basiert darauf, dass nicht ein einheitlicher Träger für die Erbringung dieser Sozialleistungen zuständig ist, s...
