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Article
Open AccessDeep learning predicts patients outcome and mutations from digitized histology slides in gastrointestinal stromal tumor
Risk assessment of gastrointestinal stromal tumor (GIST) according to the AFIP/Miettinen classification and mutational profiling are major tools for patient management. However, the AFIP/Miettinen classificati...
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Article
Prognostic factors of the synovial sarcoma of the extremities: imaging does matter
Synovial sarcomas (SS) of the extremities are rare soft tissue sarcomas that are more common in young adults. We deciphered the imaging phenotype of SS with the aim to determine if imaging could provide an inc...
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Article
Open AccessOverall survival in patients with re-excision of positive microscopic margins of limb and trunk wall soft tissue sarcoma operated outside of a reference center: a nationwide cohort analysis
This French nationwide NETSARC exhaustive prospective cohort aims to explore the impact of systematic re-excision (RE) as adjuvant care on overall survival (OS), local recurrence free survival (LRFS), and loca...
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Article
Identification of a novel translocation producing an in-frame fusion of TAF15 and ETV4 in a case of extraosseous Ewing sarcoma revealed in the prenatal period
Ewing sarcoma (ES) is a highly malignant round cell sarcoma, characterized by gene fusion involving FET (FUS, EWSR1, TAF15) and ETS family genes, respectively. The involvement of the EWSR1 gene has been reported ...
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Article
Open AccessDeterminants of the access to remote specialised services provided by national sarcoma reference centres
Spatial inequalities in cancer management have been evidenced by studies reporting lower quality of care or/and lower survival for patients living in remote or socially deprived areas. NETSARC+ is a national r...
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Article
Open AccessSoft Tissue Special Issue: Perivascular and Vascular Tumors of the Head and Neck
Perivascular and vascular neoplasms of the head and neck are a rare group of tumors comprising a spectrum of clinical/biologic and histological features. They are frequently diagnostically challenging, due to ...
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Epithelioid Hemangioendothelioma
This chapter summarizes the best of knowledge about pathological features, clinical and radiological presentation and outcome of both children and adult epithelioid hemangioendothelioma (EHE). Most of EHE disp...
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Article
Open AccessIntegrated molecular characterization of chondrosarcoma reveals critical determinants of disease progression
Chondrosarcomas are primary cancers of cartilaginous tissue with highly contrasting prognoses. These tumors are defined by recurrent mutations in the IDH genes and other genetic alterations including inactivat...
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Article
Open AccessPersistent response to vemurafenib in metastatic ameloblastoma with BRAF mutation: a case report
Ameloblastomas are uncommon locally aggressive tumors of odontogenic epithelium that rarely metastasize. Currently, there is no standard of care for the metastatic forms. Several studies have shown that amelob...
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Article
Using biology to guide the treatment of sarcomas and aggressive connective-tissue tumours
Sarcomas are a heterogeneous group of malignancies that arise from cells of a mesenchymal origin. Surgery forms the mainstay of the treatment of most patients with localized sarcoma and might be followed or pr...
