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  1. Article

    Open Access

    Perioperative goal-directed therapy and postoperative complications in different kind of surgical procedures: an updated meta-analysis

    Goal-directed therapy (GDT) aims to assure tissue perfusion, by optimizing doses and timing of fluids, inotropes, and vasopressors, through monitoring of cardiac output and other basic hemodynamic parameters. ...

    Mariateresa Giglio, Giandomenico Biancofiore in Journal of Anesthesia, Analgesia and Criti… (2021)

  2. Article

    Open Access

    Hemodynamic goal-directed therapy and postoperative kidney injury: an updated meta-analysis with trial sequential analysis

    Perioperative goal-directed therapy (GDT) reduces the risk of renal injury. However, several questions remain unanswered, such as target, kind of patients and surgery, and role of fluids and inotropes. We ther...

    Mariateresa Giglio, Lidia Dalfino, Filomena Puntillo, Nicola Brienza in Critical Care (2019)

  3. Article

    Open Access

    The effects of goal-directed fluid therapy based on dynamic parameters on post-surgical outcome: a meta-analysis of randomized controlled trials

    Dynamic predictors of fluid responsiveness, namely systolic pressure variation, pulse pressure variation, stroke volume variation and pleth variability index have been shown to be useful to identify in advance...

    Jan Benes, Mariateresa Giglio, Nicola Brienza, Frederic Michard in Critical Care (2014)

  4. Article

    Open Access

    Oral nystatin prophylaxis in surgical/trauma ICU patients: a randomised clinical trial

    Candida prophylaxis in ICU is still a matter of debate. Oral chemoprophylaxis has been advocated to reduce the incidence of Candida colonisation and infection.

    Mariateresa Giglio, Giuseppina Caggiano, Lidia Dalfino, Nicola Brienza in Critical Care (2012)