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    Cannabinoids and gene expression during brain development

    Cannabis is the most commonly used illicit drug in western societies, in particular among young people. It is consumed even by women during pregnancy and lactation, which result in a variety of disturbances in...

    Javier Fernández-ruiz, María Gómez, Mariluz Hernández in Neurotoxicity Research (2004)

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    Loss of cannabinoid CB1 receptors in the basal ganglia in the late akinetic phase of rats with experimental Huntington’s disease

    We have recently examined the status of the endocannabinoid transmission in the basal ganglia in Huntington’s disease (HD) using a rat model generated by bilateral intrastriatal injections of 3-nitropropionic ...

    Isabel Lastres-Becker, María Gómez, Rosario de Miguel in Neurotoxicity Research (2002)

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    Changes in prodynorphin and POMC gene expression in several brain regions of rat fetuses prenatally exposed to Δ-tetrahydrocannabinol

    Recently, we demonstrated that prenatal Δ-tetrahydrocannabinol (Δ9-THC) exposure alters proenkephalin mRNA levels in several brain regions of rat fetuses. In the present study, we analyzed mRNA levels of the two ...

    Alberto Pérez-Rosado, María Gómez, Jorge Manzanares in Neurotoxicity Research (2002)

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    Endogenous polyamines modulate Ca2+ channel activity in guinea-pig intestinal smooth muscle

    The polyamines spermine and spermidine inhibit L-type Ca2+ channels in whole-cell recordings from guinea-pig ileum cells (Gomez and Hellstrand, Pflügers Arch, 430:501–507, 1995 [4]). To study whether they modula...

    Maria Gomez, Per Hellstrand in Pflügers Archiv (1999)

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    Identification of a novel inflammation-protective locus in the Fischer rat

    Inbred LEW/N rats are relatively susceptible, while histocompatible inbred F344/N rats are relatively resistant to development of a wide variety of inflammatory diseases in response to a range of pro-inflamma...

    Samuel Listwak, Ruth M. Barrientos, George Koike, Soumitra Ghosh in Mammalian Genome (1999)

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    Effects of polyamines on voltage-activated calcium channels in guinea-pig intestinal smooth muscle

    Effects of polyamines on the spontaneous mechanical and electrical activity of guinea-pig intestinal smooth muscle were studied. Spermine and spermidine inhibited action potential generation and contractions, ...

    Maria Gomez, Per Hellstrand in Pflügers Archiv (1995)