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Article
Open AccessDependency and frailty in the older haemodialysis patient
Frailty among older adults undergoing hemodialysis is increasingly prevalent, significantly impacting cognitive function, mobility, and social engagement. This study focuses on the clinical profiles of very ol...
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Article
Haematology and biochemistry in healthy llamas at sea level
In the last years, there has been an increasing interest in llamas, not only as part of a productive system, but mostly as companion animals. Most reports regarding clinical biochemistry and haematology includ...
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Chapter and Conference Paper
3D Non-periodic Masonry Texture Generation of Cultural Heritage Structures
Block-based models, which can account for the actual block-by-block masonry texture, are becoming more commonly used for the analysis of historical masonry structures, given their high accuracy in representing...
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Article
“It just made me feel better”: qualitative examination of the implementation of a novel virtual psychosocial support program for adolescents with cancer
Adolescents with cancer routinely report feelings of isolation and exclusion, including from medical decision-making. To address this problem and support adolescents, we designed and implemented the novel, vir...
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Article
Open AccessIsolation of cellulose microfibers and nanofibers by mechanical fibrillation in a water-free solvent
Cellulose from vegetable sources is the most abundant biopolymer on earth. In plants, cellulose is a reinforcement element that conforms to a hierarchical structure. Cellulose micro-/nanofibers can be isolated...
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Chapter
Next-Generation Fashion Ecosystem: A STVgoDigital Approach
STVgoDigital Fashion Ecosystem 4.0 Project aims to support the Next Generation Fashion Ecosystem. The main goal of this project is to develop a digital ecosystem that brings together the main stakeholders of t...
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Article
Synthesis and characterization of microporous carbon matrix enriched by MnO2 nanoparticles
Nanocomposites (RF/MnO2) based on resorcinol–formaldehyde (RF) as carbon matrix and manganese oxide nanoparticles (MnO2) as incorporated material were elaborated by a sol–gel method. The effect of pyrolysis tempe...
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Article
Open AccessLow-level constitutional mosaicism of BRCA1 in two women with young onset ovarian cancer
Germline pathogenic variants in BRCA1 and BRCA2 cause hereditary breast and ovarian cancer. The vast majority of these variants are inherited from a parent. De novo constitutional pathogenic variants are rare. Ev...
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Article
Open AccessPI3K-AKT, JAK2-STAT3 pathways and cell–cell contact regulate maspin subcellular localization
Maspin (SERPINB5) is a potential tumor suppressor gene with pleiotropic biological activities, including regulation of cell proliferation, death, adhesion, migration and gene expression. Several studies indica...
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Article
Gevuina avellana and Lomatia dentata, two Proteaceae species from evergreen temperate forests of South America exhibit contrasting physiological responses under nutrient deprivation
Gevuina avellana and Lomatia dentata are Proteaceae species from evergreen temperate forests, but only G. avellana can colonize nutrient deprived volcanic depositions. We hypothesized that under nutrient deprivat...
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Article
Open AccessStop** targeted therapy for complete responders in advanced BRAF mutant melanoma
BRAF inhibitors revolutionised the management of melanoma patients and although resistance occurs, there is a subgroup of patients who maintain durable disease control. For those cases with durable complete re...
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Article
The mediator role of unmet needs on quality of life in myeloma patients
The diagnosis of multiple myeloma (MM) has a significant impact on patients. This study analyzed the mediating role of patients’ unmet needs in the relationship between psychological morbidity/social support a...
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Article
Robust resistive switching performance of pulsed laser deposited SiC/Ag/SiC tri-layer thin films deposited on a glass substrate
In this work, the authors developed SiC(10 nm)/Ag/SiC(10 nm) thin films showing an electroforming-free resistive switching (RS) effect with a switching ratio of 102. The observed RS effect is attributed to chargi...
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Article
Substrate Temperature Effect on Microstructure, Optical, and Glucose Sensing Characteristics of Pulsed Laser Deposited Silver Nanoparticles
This work reports the substrate temperature-influenced change in the structural, morphological, optical, and glucose sensing properties of silver (Ag) nanoparticles (NPs) deposited on p-type Si (100) wafers. A...
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Article
Norm Convergence of Self-Adjoint Extensions of the Aharonov–Bohm Hamiltonian as Solenoid Length Goes to Infinity
With respect to the Aharonov-Bohm effect, we consider only solenoids of zero radius and their action on its plane of symmetry. We find all self-adjoint extensions in case of finite length solenoids and compare...
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Article
Open AccessEnhanced resistive switching characteristics in Pt/BaTiO3/ITO structures through insertion of HfO2:Al2O3 (HAO) dielectric thin layer
An enhanced resistive switching (RS) effect is observed in Pt/BaTiO3(BTO)/ITO ferroelectric structures when a thin HfO2:Al2O3 (HAO) dielectric layer is inserted between Pt and BTO. The P-E hysteresis loops reveal...
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Article
Evaluation of deep gray matter volume, cortical thickness and white matter integrity in patients with typical absence epilepsy: a study using voxelwise-based techniques
The objective of this study was to evaluate the cortical thickness and the volume of deep gray matter structures, measured from 3D T1-weighted gradient echo imaging, and white matter integrity, by diffusion te...
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Article
Open AccessSclerostin does not play a major role in the pathogenesis of skeletal complications in type 2 diabetes mellitus
In contrast to previously reported elevations in serum sclerostin levels in diabetic patients, the present study shows that the impaired bone microarchitecture and cellular turnover associated with type 2 diab...
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Article
Breakwater control system and structural analysis: physical and numerical modelling (Port of Funchal, Madeira Island, Portugal)
The objective of this work was to analyze the behavior of the Funchal Port (Madeira Island, Portugal) breakwater using physical and numerical models in order to analyze the evolution of the underwater layers, ...
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Article
Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells
Mesenchymal stromal cells (MSCs) have been shown to reverse radiation damage to marrow stem cells. We have evaluated the capacity of MSC-derived extracellular vesicles (MSC-EVs) to mitigate radiation injury to...