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Article
Open AccessCytogenetic bio-dosimetry techniques in the detection of dicentric chromosomes induced by ionizing radiation: A review
Ionizing radiation is ubiquitous in the environment. Its source can be natural, such as radioactive materials present in soil and cosmic rays, or artificial, such as the fuel for nuclear power plants. Overexpo...
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Article
Assessing two-way interactions between cells and inorganic nanoparticles
A safe and effective use of nanoparticles in biology and medicine requires a thorough understanding, down to the molecular level, of how nanoparticles interact with cells in the physiological environment. This...
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Article
Effect of chitosan and dextran on the properties of poly(vinyl alcohol) hydrogels
Hydrogels are three-dimensional polymeric networks very similar to biological tissues and potentially useful as drug delivery systems. Poly(vinyl alcohol)-based hydrogels containing different amounts of dextra...
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Article
Hydrogels based on chitosan and dextran as potential drug delivery systems
The release of human growth hormone (GH) from bioartificial polymeric materials in the form of hydrogels, was measured in vitro for up to 3 weeks. Poly(vinyl-alcohol) (PVA) was blended, in different ratios, wi...
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Article
Dehydro-thermally cross-linked collagen-poly(vinyl alcohol) blends: mechanical, biological and surface properties
The mechanical, biological and surface properties of films, based on blends of soluble collagen and poly(vinyl alcohol), were investigated. Films prepared by casting were cross-linked by a dehydro-thermal trea...
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Article
Optimization of the interaction between ethylenevinyl alcohol copolymers and human endothelial cells
To better understand and optimize the fine interactions that occur during adhesion events between human cells and synthetic materials, we seeded human umbilical vein endothelial cells (HUVEC) onto ethylene-vin...
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Article
Evaluation of poly(vinyl alcohol) hydrogels as a component of hybrid artificial tissues
Hydrogels are three-dimensional polymeric networks very similar to biological tissues. Many synthetic polymers can be used in preparing hydrogels. Among them poly(vinyl alcohol) (PVA), physically crosslinked b...
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Article
Physico-chemical and mechanical characterization of hydrogels of poly (vinyl alcohol) and hyaluronic acid
Hydrogels are three-dimensional polymeric networks very similar to biological tissues and potentially useful as soft tissue substitutes and drug delivery systems. Many synthetic polymers can be used to make hy...
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Article
Collagen-based bioartificial materials—evaluation as membranes for extracorporeal blood purification
The preparation of films from blends of collagen and poly(vinyl alcohol) is described and the transport properties of these films are evaluated. Different crosslinking procedures, dehydrothermal crosslinking a...
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Article
Collagen and hyaluronic acid based polymeric blends as drug delivery systems for the release of physiological concentrations of growth hormone
Two synthetic polymers, poly(vinyl alcohol) (PVA) and poly(acrylic acid) (PAA) were blended, in different ratios, with two biological polymers, collagen (C) and hyaluronic acid (HA). These blends were used to ...
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Article
Biological characterization of hydrogels of poly(vinyl alcohol) and hyaluronic acid
Hydrogels of hyaluronic acid (HA) and poly(vinyl alcohol) (PVA) were prepared using eight freezing-thawing cycles from HA/PVA blends (10/90, 20/80, 30/70, 40/60, 50/50, and 0/100 (w/w) ratios). The biocompatib...
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Article
In vitro biocompatibility of fluorinated polyurethanes
The in vitro biocompatibility of fluorinated polyurethanes (FPUs), labelled as FPU 42, 52, 58, and 60, was evaluated by means of thrombogenicity, cytoxicity and cytocompatibility tests. Cardiothane® was taken as ...
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Article
Block copolymers of L-lactide and poly(ethylene glycol) for biomedical applications
Poly (L-lactide)-poly (oxyethylene)-poly (L-lactide) block copolymers obtained in bulk, by a ring opening mechanism, from poly (ethylene glycol)s (PEG)s and L-lactide (LA), at 120–140°C, in the absence of adde...
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Article
Poly(ester-ether-ester) block copolymers as biomaterials
Poly(ester-ether-ester) block copolymers, belonging to a class of biodegradable materials, were synthesized from poly(ethylene glycol) and ε-caprolactone by a simple ring-opening mechanism, which avoids the us...
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Article
Cell cultures in the biocompatibility study of synthetic materials
In vitro cytotoxicity (Neutral Red uptake, Kenacid Blue and MTT) and cytocompatibility (cell adhesion and proliferation) tests were applied to the biocompatibility study of a series of poly(ester-ether-ester) bl...