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Article
Assessing two-way interactions between cells and inorganic nanoparticles
A safe and effective use of nanoparticles in biology and medicine requires a thorough understanding, down to the molecular level, of how nanoparticles interact with cells in the physiological environment. This...
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Article
Transglutaminase Reactivity with Gelatine: Perspective Applications in Tissue Engineering
Gelatine was crosslinked by means of an enzymatic treatment using tissue transglutaminase (tTGase) (Sigma) and microbial transglutaminase (mTGase) (A**omoto) which catalyses the formation of isopeptide bonds ...
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Article
Composites between hydroxyapatite and poly(ε-caprolactone) synthesized in open system at room temperature
The hydroxyls present on the surface of hydroxyapatite (HA) granules, annealed at 700 ∘, 900 ∘ and 1100 ∘C, are able to initiate the polymerization of ε-caprolactone (CL), not only at 185 ∘C under vacuum, but ...
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Article
Fibers by bioresorbable poly(ester-ether-ester)s as potential suture threads: a preliminary investigation
Fibers made by a bioresorbable poly(ε-caprolactone)-block-poly(oxyethylene)-block-poly(ε-caprolactone) copolymer, having a number average molecular mass of about 200 000 Da and an average molar composition of ...
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Article
Effect of chitosan and dextran on the properties of poly(vinyl alcohol) hydrogels
Hydrogels are three-dimensional polymeric networks very similar to biological tissues and potentially useful as drug delivery systems. Poly(vinyl alcohol)-based hydrogels containing different amounts of dextra...
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Article
Dehydro-thermally cross-linked collagen-poly(vinyl alcohol) blends: mechanical, biological and surface properties
The mechanical, biological and surface properties of films, based on blends of soluble collagen and poly(vinyl alcohol), were investigated. Films prepared by casting were cross-linked by a dehydro-thermal trea...
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Article
Physico-chemical and mechanical characterization of hydrogels of poly (vinyl alcohol) and hyaluronic acid
Hydrogels are three-dimensional polymeric networks very similar to biological tissues and potentially useful as soft tissue substitutes and drug delivery systems. Many synthetic polymers can be used to make hy...
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Article
Physical and biological stability of dehydro-thermally crosslinked collagen—poly(vinyl alcohol) blends
Dehydro-thermal treatments for 3, 24 and 72 h were used to crosslink blends of collagen and poly(vinyl alcohol) with various compositions. This crosslinking method increases the biological stabilityin vitro of co...
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Article
Blends of hyaluronic acid derivatives with ethylene-vinyl alcohol copolymers as potential biomaterials
Films were prepared by solution casting from blends of hyaluronic acid derivatives and ethylene-vinyl alcohol copolymers. A chemico-physical and biological characterization was carried out on these “bioartific...
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Article
Collagen-based bioartificial materials—evaluation as membranes for extracorporeal blood purification
The preparation of films from blends of collagen and poly(vinyl alcohol) is described and the transport properties of these films are evaluated. Different crosslinking procedures, dehydrothermal crosslinking a...
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Article
Preparation and characterization of permselective, biocompatible membranes for the macroencapsulation of pancreatic islets
Polymeric membranes were prepared by mixing poly (vinyl alcohol) (PVA) and poly (acrilic acid) (PAA) solutions (10/90 weight ratio), freeze-drying and crosslinking under vacuum. The membranes were then coated ...
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Article
Biological characterization of hydrogels of poly(vinyl alcohol) and hyaluronic acid
Hydrogels of hyaluronic acid (HA) and poly(vinyl alcohol) (PVA) were prepared using eight freezing-thawing cycles from HA/PVA blends (10/90, 20/80, 30/70, 40/60, 50/50, and 0/100 (w/w) ratios). The biocompatib...
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Article
Hydrogels of poly(vinyl alcohol) and collagen as new bioartificial materials
Poly(vinyl alcohol) was used to make hydrogels containing various amounts of collagen. These “bioartificial materials”, made of synthetic and biological polymers, were studied to investigate the effect of the ...