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Article
Heparan sulphate proteoglycans are essential for the myeloma cell growth activity of EGF-family ligands in multiple myeloma
The epidermal growth factor (EGF)/EGF-receptor (ErbB1-4) family is involved in the biology of multiple myeloma (MM). In particular, ErbB-specific inhibitors induce strong apoptosis of myeloma cells (MMC) in vitro
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Article
Anti-CD20 antibody as consolidation therapy in a patient with primary plasma cell leukemia after high-dose therapy and autologous stem cell transplantation
In multiple myeloma (MM), circulating malignant B cells are proposed as the proliferative compartment of the disease. In view of the close relationship between multiple myeloma and primary plasma cell leukemi...
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Article
CD19+ and CD20+ B cells from the peripheral blood of patients with multiple myeloma are not infected with human herpesvirus 8
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Article
The remission status before and the PCR status after high-dose therapy with peripheral blood stem cell support are prognostic factors for relapse-free survival in patients with follicular non-Hodgkin’s lymphoma
It was the aim of our study to examine the clinical significance of t(14;18)-positive cells in samples from 47 patients with follicular non-Hodgkin’s lymphoma (NHL) who underwent high-dose therapy with autolog...
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Chapter and Conference Paper
Myeloablative Hochdosistherapie mit Blutstammzellentransplantation bei Patienten mit zentroblastisch-zentrozytischem Non-Hodgkin-Lymphom
Zentroblastisch-zentrozytische (CB-CC-)Non-Hodgkin-Lymphome (NHL) werden nach der Kiel-Klassifikation [9] aufgrund pathomorphologischer Kriterien und ihres klinischen Verlaufes als niedrigmaligne eingestuft [1...
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Chapter and Conference Paper
Fluorescence In Situ Hybridization for the Diagnosis and Follow-up of BCR-ABL Positive ALL
The BCR-ABL fusion, which is the molecular counterpart of the t(9;22), is the most common genetic abnormality in adult acute lymphoblastic leukemia (ALL) [1]. Due to its important diagnostic and prognostic sig...
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Chapter and Conference Paper
Designing Probe Sets for the Detection of Chromosome Abnormalities in Acute Myeloid Leukemia Using Fluorescence In Situ Hybridization
In recent years, the karyotype as a prognostic factor in acute myeloid leukemia (AML) has gained considerable interest. Clonal chromosome aberrations are identified in 50–60% of patients with AML (for review s...
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Article
Detection of minimal tumor load in blood stem cell autografts in multiple myeloma: Steady-state versus high-dose chemotherapy stem cell mobilization
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Article
Abstract