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Open AccessSystems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C
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Open AccessAntigen-specific T lymphocyte responses elicited by a DNA – MVA HIV CN54gp140 immunization regime are significantly altered by the TLR4 adjuvant GLA
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Open AccessImmune responses triggered by HIV/AIDS vaccine candidates, derived from MVA-B, with deletions in several immune regulatory genes
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Open AccessComparison of the depth of vaccine-elicited HIV-1 Env epitope-specific CD8+ T lymphocyte responses
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Open AccessP17-23. Enhanced expression of HIV antigens and improved antigen presentation after infection with replication competent attenuated vaccinia virus in vitro
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Open AccessP17-07. Insertion of a vaccinia virus host range (hr) gene into NYVAC-B genome potentiates immune responses against HIV-1 antigens
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Open AccessP02-04. Multimeric soluble CD40 ligand efficiently enhances HIV specific cellular immune responses during DNA prime and boost with attenuated poxvirus strains
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Role of mitochondria in apoptosis induced by the 2‐5A system and mechanisms involved
The 2‐5A system (2-5OAS/RNaseL) is composed of the 2′,5′oligoadenylate synthetase 1 (2-5OAS1) and 2-5A-dependent RNase (RNaseL), enzymes that play a key role in antiviral defence mechanisms. Activation of the ...
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Tissue distribution of the Ankara strain of vaccinia virus (MVA) after mucosal or systemic administration
MVA is a candidate vector for vaccination against pathogens and tumors. Little is known about its behaviour in mucosal tissues. We have investigated the fate and biosafety of MVA, when inoculated by different...
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Visna/maedi virus Env protein expressed by a vaccinia virus recombinant induces cell-to-cell fusion in cells of different origins in the apparent absence of Env cleavage: role of glycosylation and of proteoglycans
The in vivo productive infection by the ovine Visna/maedi lentivirus (VISNA) is restricted to cells of the monocyte/macrophage lineage. The basis for this restriction is not understood. Although the VISNA envelo...
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Recombinant proteins produced by vaccinia virus vectors can be incorporated within the virion (IMV form) into different compartments
Vaccinia virus (VV) is one of the largest and most complex of animal viruses, with a virion that contains about 100 different polypeptides. Assembly of the viral proteins occurs in discrete cytoplasmic sites ...
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Antiviral activity of a synthetic analog of prostaglandin A in mice infected with influenza A virus
We have previously shown that prostaglandins of the A series potently inhibit virus replication in several virus-host systems in vitro. In the present report we have studied the effect of a long-acting synthet...
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Studies on the mechanism of entry of vaccinia virus in animal cells
In order to study the mechanism of entry of vaccinia virus into cells the fate of virion associated polypeptides was investigated during infection of african green monkey kidney (BSC-40) cells with 35 S-methio...
